Evidence map›Paper›PMID 31842758›Full record

ArticleBMC cardiovascular disorders2019

The concentration of resistin in perivascular adipose tissue after CABG and postoperative atrial fibrillation.

Maciej Rachwalik, Marta Obremska, Dorota Zyśko, Małgorzata Matusiewicz, Krzysztof Ściborski, Marek Jasiński

Open access · goldAbstract read
In one paragraph

Article in BMC cardiovascular disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maciej RachwalikDepartment and Clinic of Cardiac Surgery, Wroclaw Medical University, ul. Borowska 213, 50-556, Wrocław, Poland. mrach@wp.pl.ORCID 0000-0001-9714-4059
Marta ObremskaDepartment and Clinic of Cardiac Surgery, Wroclaw Medical University, ul. Borowska 213, 50-556, Wrocław, Poland.
Dorota ZyśkoDepartment and Clinic of Emergency Medicine, Wroclaw Medical University, Wroclaw, Poland.
Małgorzata MatusiewiczDepartment of Medical Biochemistry, Wroclaw Medical University, Wroclaw, Poland.
Krzysztof ŚciborskiDepartment and Clinic of Cardiology, Wroclaw Medical University, Wroclaw, Poland.
Marek JasińskiDepartment and Clinic of Cardiac Surgery, Wroclaw Medical University, ul. Borowska 213, 50-556, Wrocław, Poland.
Wroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative atrial fibrillation occurs in up to 30% of patients after coronary artery bypass graft (CABG) and its cause is unknown. The aim of the study was to evaluate whether concentration of resistin in surrounding coronary artery perivascular adipose tissue (PVAT) is related to postoperative atrial fibrillation occurrence.

methodsA total number of 46 patients (35 male, 11 female; median age 66.5) were qualified for elective CABG. Medical history, laboratory test results and echocardiographic parameters were noted. Patients were monitored up to 3 days after CABG and then were divided into groups with and without postoperative atrial fibrillation occurrence. Fragments of PVAT were collected intra-operatively: near the left anterior descending artery and main left coronary artery. The concentration of resistin was determined by Human Resistin Quantikine ELISA Kit and expressed as ng/g. A multivariate stepwise logistic regression analysis was performed to find variables related to postoperative atrial fibrillation occurrence.

resultsPostoperative atrial fibrillation occurred in 14 (30.4%) patients. The patients with and without postoperative atrial fibrillation were similar in age, gender, epicardial adipose tissue thickness and laboratory parameters. The concentration of resistin in PVAT near the left main coronary artery was significantly higher in patients with postoperative atrial fibrillation than in those without the complication (P = 0.03). In the multivariate stepwise logistic regression analysis the concentration of resistin above cut-off point 54 ng/g in PVAT near left main coronary artery was independently related to postoperative atrial fibrillation occurrence (OR: 7.7; 95% CI:1.4-42.2 p = 0.02).

conclusionsThe higher concentrations of resistin in PVAT near the left main coronary artery which is located close to the left atrium are associated with postoperative atrial fibrillation.

Indexed as

Adipose TissueAgedAtrial FibrillationCoronary Artery BypassFemaleHumansMaleMiddle AgedResistinRisk FactorsTreatment OutcomeUp-RegulationResistinRETN protein, humanCoronary artery bypass graftPostoperative atrial fibrillationResistin

Identifiers

PMID31842758
PMCPMC6915954
OpenAlexW2996156961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.