Evidence map›Paper›PMID 31842516›Full record

ArticleInternational journal of molecular sciences2019

Genetic Programs Driving Oncogenic Transformation: Lessons from in Vitro Models.

Eros Di Giorgio, Harikrishnareddy Paluvai, Raffaella Picco, Claudio Brancolini

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. In Silico Logical Modelling to Uncover Cooperative Interactions in Cancer.International journal of molecular sciences · 2021
    Review
  3. Basic and Translational Models of Cooperative Oncogenesis.International journal of molecular sciences · 2020
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Eros Di GiorgioDepartment of Medicine, Università degli Studi di Udine, P.le Kolbe 4, 33100 Udine, Italy.
Harikrishnareddy PaluvaiDepartment of Medicine, Università degli Studi di Udine, P.le Kolbe 4, 33100 Udine, Italy.
Raffaella PiccoDepartment of Medicine, Università degli Studi di Udine, P.le Kolbe 4, 33100 Udine, Italy.
Claudio BrancoliniDepartment of Medicine, Università degli Studi di Udine, P.le Kolbe 4, 33100 Udine, Italy.
University of Udine · IT

Funding

Regione Autonoma Friuli Venezia Giulia COLONACT
6 · The paper itself

Abstract

Cancer complexity relies on the intracellular pleiotropy of oncogenes/tumor suppressors and in the strong interplay between tumors and micro- and macro-environments. Here we followed a reductionist approach, by analyzing the transcriptional adaptations induced by three oncogenes (

Indexed as

Genetic Predisposition to DiseaseOncogenesAnimalsBiomarkersCell Transformation, NeoplasticDatabases, GeneticGene Expression Regulation, NeoplasticHumansIn Vitro TechniquesNeoplasmsPrognosisSignal TransductionBiomarkersDOCK4G0S2HDAC4inflammationMYCRASSRPX interferonTCGA

Identifiers

PMID31842516
PMCPMC6940909
OpenAlexW2994798519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.