Evidence map›Paper›PMID 31842486›Full record

ArticleCancers2019

Prediction of Colon Cancer Stages and Survival Period with Machine Learning Approach.

Pushpanjali Gupta, Sum-Fu Chiang, Prasan Kumar Sahoo, Suvendu Kumar Mohapatra, Jeng-Fu You, Djeane Debora Onthoni, Hsin-Yuan Hung, Jy-Ming Chiang, Yenlin Huang, Wen-Sy Tsai

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Role of circAGFG1 as an oncogene in triple-negative breast cancer.Apoptosis : an international journal on programmed cell death · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Expression of VISTA on T cells in patients with cancer colon.Journal of the Egyptian National Cancer Institute · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Pushpanjali GuptaDepartment of Computer Science and Information Engineering, Chang Gung University, Guishan 33302, Taiwan.ORCID 0000-0002-6077-9701
Sum-Fu ChiangDivision of Colon and Rectal Surgery, Chang Gung Memorial Hospital, Linkou 33305, Taiwan.ORCID 0000-0001-8753-0239
Prasan Kumar SahooDepartment of Computer Science and Information Engineering, Chang Gung University, Guishan 33302, Taiwan.ORCID 0000-0003-3496-1195
Suvendu Kumar MohapatraVolktek Corporation, New Taipei 23553, Taiwan.
Jeng-Fu YouDivision of Colon and Rectal Surgery, Chang Gung Memorial Hospital, Linkou 33305, Taiwan.
Djeane Debora OnthoniDepartment of Computer Science and Information Engineering, Chang Gung University, Guishan 33302, Taiwan.
Hsin-Yuan HungDivision of Colon and Rectal Surgery, Chang Gung Memorial Hospital, Linkou 33305, Taiwan.
Jy-Ming ChiangDivision of Colon and Rectal Surgery, Chang Gung Memorial Hospital, Linkou 33305, Taiwan.
Yenlin HuangCollege of Medicine, Chang Gung University, Guishan 33302, Taiwan.
Wen-Sy TsaiDivision of Colon and Rectal Surgery, Chang Gung Memorial Hospital, Linkou 33305, Taiwan.
Chang Gung University · TWChang Gung Memorial Hospital · TW

Funding

CHANG GUNG MEDICAL FOUNDATION, TAIWAN CMRPD2H0291Ministry of Science and Technology, Taiwan 108-2221-E-182-050
6 · The paper itself

Abstract

The prediction of tumor in the TNM staging (tumor, node, and metastasis) stage of colon cancer using the most influential histopathology parameters and to predict the five years disease-free survival (DFS) period using machine learning (ML) in clinical research have been studied here. From the colorectal cancer (CRC) registry of Chang Gung Memorial Hospital, Linkou, Taiwan, 4021 patients were selected for the analysis. Various ML algorithms were applied for the tumor stage prediction of the colon cancer by considering the Tumor Aggression Score (TAS) as a prognostic factor. Performances of different ML algorithms were evaluated using five-fold cross-validation, which is an effective way of the model validation. The accuracy achieved by the algorithms taking both cases of standard TNM staging and TNM staging with the Tumor Aggression Score was determined. It was observed that the Random Forest model achieved an F-measure of 0.89, when the Tumor Aggression Score was considered as an attribute along with the standard attributes normally used for the TNM stage prediction. We also found that the Random Forest algorithm outperformed all other algorithms, with an accuracy of approximately 84% and an area under the curve (AUC) of 0.82 ± 0.10 for predicting the five years DFS.

Indexed as

artificial intelligencecolon cancerdisease-free survivalmachine learningpredictionTNM staging

Identifiers

PMID31842486
PMCPMC6966646
OpenAlexW2995579012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.