Evidence map›Paper›PMID 31842352›Full record

ReviewCancers2019

The Genetic Architecture of Gliomagenesis-Genetic Risk Variants Linked to Specific Molecular Subtypes.

Wendy Yi-Ying Wu, Gunnar Johansson, Carl Wibom, Thomas Brännström, Annika Malmström, Roger Henriksson, Irina Golovleva, Melissa L Bondy, Ulrika Andersson, Anna M Dahlin and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Wendy Yi-Ying WuDepartment of Radiation Sciences, Oncology, Umeå University, 901 87 Umeå, Sweden.ORCID 0000-0002-6169-5155
Gunnar JohanssonDepartment of Radiation Sciences, Oncology, Umeå University, 901 87 Umeå, Sweden.
Carl WibomDepartment of Radiation Sciences, Oncology, Umeå University, 901 87 Umeå, Sweden.ORCID 0000-0001-8851-2905
Thomas BrännströmDepartment of Medical Bioscience, Umeå University, 901 87 Umeå, Sweden.
Annika MalmströmDepartment of Advanced Home Care, Linköping University and Department of Clinical and Experimental Medicine, Linköping University, 581 83 Linköping, Sweden.ORCID 0000-0001-8410-4939
Roger HenrikssonDepartment of Radiation Sciences, Oncology, Umeå University, 901 87 Umeå, Sweden.
Irina GolovlevaDepartment of Medical Bioscience, Umeå University, 901 87 Umeå, Sweden.
Melissa L BondyDepartment of Health Research and Policy (Epidemiology), Stanford University School of Medicine, Stanford, CA 94305, USA.
Ulrika AnderssonDepartment of Radiation Sciences, Oncology, Umeå University, 901 87 Umeå, Sweden.
Anna M DahlinDepartment of Radiation Sciences, Oncology, Umeå University, 901 87 Umeå, Sweden.
Beatrice MelinDepartment of Radiation Sciences, Oncology, Umeå University, 901 87 Umeå, Sweden.
Umeå University · SEBaylor College of Medicine · USLinköping University · SE

Funding

International Case Control Study of Malignant GliomaR01CA139020 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BONDY, MELISSA L. · 2010 to 2015
$16.0M
PHYSICAL AND BIOLOGICAL APPROACHES TO Z-DNAK04CA001159 · NCI · LEHIGH UNIVERSITY · PI BEHE, MICHAEL J · 1985 to 1988
–
NCI NIH HHS R01CA139020/CA/NCINorthern Sweden Research Foundation AMP 16-805Swedish Cancer Foundation CAN 2018/390Swedish Research Council 2016-01159_3Umeå University Hospital Grant BAS-ALF: 7002485Umeå University Hospital Grant Central-ALF: 7002994
6 · The paper itself

Abstract

Genome-wide association studies have identified 25 germline genetic loci that increase the risk of glioma. The somatic tumor molecular alterations, including

Indexed as

1p/19q co-deletionetiopathogenesisgenotype phenotypegliomagliomagenesisIDH mutant

Identifiers

PMID31842352
PMCPMC6966482
OpenAlexW2996524677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.