Evidence map›Paper›PMID 31842340›Full record

ArticleMolecules (Basel, Switzerland)2019

Synthesis and Characterization of New Multifunctional Self-Boosted Filters for UV Protection: ZnO Complex with Dihydroxyphenyl Benzimidazole Carboxylic Acid.

Mattia Battistin, Elisa Durini, Valeria Dissette, Alessandro Bonetto, Antonio Marcomini, Elisa Casagrande, Andrea Brunetta, Paola Ziosi, Sonia Molesini, Riccardo Gavioli and 4 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mattia BattistinDepartment of Life Sciences and Biotechnology, Master Course in Cosmetic Science and Technology (COSMAST), University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.
Elisa DuriniDepartment of Life Sciences and Biotechnology, Master Course in Cosmetic Science and Technology (COSMAST), University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.
Valeria DissetteDepartment of Life Sciences and Biotechnology, Master Course in Cosmetic Science and Technology (COSMAST), University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.ORCID 0000-0002-8862-5130
Alessandro BonettoDepartment of Environmental Sciences, Informatic and Statistics, University Ca' Foscari Venice, Vegapark, Via delle Industrie 21/8, 30175 Marghera, Venice, Italy.
Antonio MarcominiDepartment of Environmental Sciences, Informatic and Statistics, University Ca' Foscari Venice, Vegapark, Via delle Industrie 21/8, 30175 Marghera, Venice, Italy.
Elisa CasagrandeDMSN - Department of Molecular Sciences and Nanosystems, University Ca' Foscari of Venice, Via Torino 155/b, 30172 Venice, Mestre, Italy.
Andrea BrunettaKalis S.r.l, Via Caodevilla 38, 31040 Onigo di Pederobba (TV), Italy.
Paola ZiosiAmbrosialab Srl, Via Mortara 171, 44121 Ferrara, Italy.
Sonia MolesiniAmbrosialab Srl, Via Mortara 171, 44121 Ferrara, Italy.
Riccardo GavioliDepartment of Chemical and Pharmaceutical Science, University of Ferrara, Via Fossato di Mortara 64/B, 44121 Ferrara, Italy.
Francesco NicoliDepartment of Chemical and Pharmaceutical Science, University of Ferrara, Via Fossato di Mortara 64/B, 44121 Ferrara, Italy.ORCID 0000-0001-6327-5958
Stefano ManfrediniDepartment of Life Sciences and Biotechnology, Master Course in Cosmetic Science and Technology (COSMAST), University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.ORCID 0000-0003-1348-4422
Silvia VertuaniDepartment of Life Sciences and Biotechnology, Master Course in Cosmetic Science and Technology (COSMAST), University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.
Anna BaldisserottoDepartment of Life Sciences and Biotechnology, Master Course in Cosmetic Science and Technology (COSMAST), University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.ORCID 0000-0002-2882-3530

Funding

Ambrosialab srl, Ferrara Grant 2017-2018Kalis srl, Cornuda, Italy Ambrosialab srl, FerrPhD fellowship of Mattia Battistin 2016-2019This work was supported by the University of Ferrara Bando FIR-2016 to Silvia Vertuani and Bando FAR 2017 to Stefano Manfredini)
6 · The paper itself

Abstract

The incidence of skin cancer is increasing both because of climate change and the increase in pollution than people's incorrect habits of sun exposure. In these regards, sunscreen and photoprotection are essential tools in consenting the benefits induced by safe solar light exposition and skin cancer prevention. In this work, a new class of sunscreen filter was synthesized by chemical combination of a physical filter (ZnO) and Oxisol (dihydroxyphenyl benzimidazole carboxylic acid), an antioxidant molecule with booster effect. In this work, a new class of filters with new properties was achieved by direct functionalization of particles surface. A full characterization of this multifunctional ingredient (ZnO-Ox) was conducted: Compared with the simple mixture, the new filter acts as a multifunctional molecule showing a higher Sun Protection Factor (SPF), a better cytotoxic profile (MTT and NRU assay), and anti-acne activity. A strong reduction of photocatalytic activity of ZnO was observed, also improving the safety profile.

Indexed as

AntioxidantsBenzimidazolesSunscreening AgentsZinc Oxide3T3 CellsAnimalsHumansMiceSkin NeoplasmsSunlightUltraviolet RaysAntioxidantsBenzimidazolesSunscreening AgentsZinc Oxideacneantioxidantmolecular combinationOxisolskin cancerSPF boostersunscreenZnO

Identifiers

PMID31842340
PMCPMC6943673

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.