Evidence map›Paper›PMID 31841384›Full record

ArticleAmerican journal of physiology. Renal physiology2020

Elucidation of cGMP-dependent induction of mitochondrial biogenesis through PKG and p38 MAPK in the kidney.

Pallavi Bhargava, Jaroslav Janda, Rick G Schnellmann

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  8. Role of the βPharmacological reports : PR · 2024
    Article
  9. Review
  10. UPROrphanet journal of rare diseases · 2022
    Article
  11. Review
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  17. βAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2021
    Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Pallavi BhargavaDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona.
Jaroslav JandaDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona.
Rick G SchnellmannDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona.
University of Arizona · US

Funding

SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI DEAN BILLHEIMER · 1994 to 2026
$36.7M
NIEHS NIH HHS P30 ES006694
6 · The paper itself

Abstract

Previous studies have shown that cGMP increases mitochondrial biogenesis (MB). Our laboratory has determined that formoterol and LY344864, agonists of the β

Indexed as

Organelle BiogenesisAnimalsCarbazolesCells, CulturedCyclic GMPCyclic GMP-Dependent Protein KinasesDibenzocycloheptenesEnzyme ActivationEnzyme ActivatorsFemaleFluorobenzenesFormoterol FumarateKidneyMitochondriap38 Mitogen-Activated Protein KinasesPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaCarbazolesCyclic GMPCyclic GMP-Dependent Protein KinasesDibenzocycloheptenesEnzyme ActivatorsFluorobenzenesFormoterol FumarateKT 5823LY 344864p38 Mitogen-Activated Protein KinasesPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaProtein Kinase InhibitorsPyrazolesPyrimidinesriociguatskepinone-LbiogenesiscGMPguanylyl cyclasemitochondriamitogen-activated protein kinaseprotein kinase Grenal repair

Identifiers

PMID31841384
PMCPMC7052650
OpenAlexW2996367052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.