Evidence map›Paper›PMID 31841258›Full record

ArticleArthritis care & research2021

How Are Neighborhood Characteristics Associated With Mental and Physical Functioning Among Older Adults With Radiographic Knee Osteoarthritis?

Sarah D Kowitt, Allison E Aiello, Leigh F Callahan, Edwin B Fisher, Nisha C Gottfredson, Joanne M Jordan, Kathryn E Muessig

Abstract readComparative Study
In one paragraph

Article in Arthritis care & research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Accelerating real-world prediction and research in Alzheimer's: The M3AD study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Depression in Osteoarthritis: Current Understanding.Neuropsychiatric disease and treatment · 2022
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sarah D KowittGillings School of Global Public Health and School of Medicine, University of North Carolina, Chapel Hill.ORCID 0000-0001-5216-3897
Allison E AielloGillings School of Global Public Health, University of North Carolina, Chapel Hill.
Leigh F CallahanGillings School of Global Public Health and School of Medicine, University of North Carolina, Chapel Hill.
Edwin B FisherGillings School of Global Public Health, University of North Carolina, Chapel Hill.
Nisha C GottfredsonGillings School of Global Public Health, University of North Carolina, Chapel Hill.
Joanne M JordanGillings School of Global Public Health and School of Medicine, University of North Carolina, Chapel Hill.ORCID 0000-0003-2469-9955
Kathryn E MuessigGillings School of Global Public Health, University of North Carolina, Chapel Hill.

Funding

UNC Core Center for Clinical ResearchP30AR072580 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LEIGH Fleming CALLAHAN, Amanda E Nelson · 2019 to 2026
$6.1M
Project 3P60AR049465 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JORDAN, JOANNE M. · 2003 to 2008
$6.0M
NIAMS Multidisciplinary Clinical Research CenterP60AR064166 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SCHWARTZ, TODD A · 2013 to 2017
$5.8M
Johnston County Osteoarthritis Project: Arthritis, Disability, and Other Chronic DiseasesU01DP006266 · DP · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NELSON, AMANDA E · 2016 to 2020
$3.8M
The Johnston County OA Project: Arthritis and DisabilityU01DP003206 · DP · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JORDAN, JOANNE M. · 2011 to 2015
$3.2M
Women's knee motion patterns in functional activitiesP60AR030701 · NIAMS · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI CALLAHAN, LEIGH FLEMING · 1986 to 2001
$1.9M
Individual & Community Social Determinants of Osteoarthritis OutcomesR01AR053989 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CALLAHAN, LEIGH FLEMING · 2008 to 2012
$1.6M
ACL HHS U01DP003206NCCDPHP CDC HHS U01 DP003206NCCDPHP CDC HHS U01 DP006266NIAMS NIH HHS P30 AR072580NIAMS NIH HHS P60 AR030701NIAMS NIH HHS P60 AR049465NIAMS NIH HHS P60 AR064166NIAMS NIH HHS R01 AR053989
6 · The paper itself

Abstract

objectiveTo examine how neighborhood characteristics are associated with health outcomes among older adults with osteoarthritis.

methodsIn multilevel, cross-sectional, and longitudinal analyses we examined whether 4 neighborhood characteristics were associated with depressive symptoms and reported knee impact scores, and whether the neighborhood characteristics interacted with race/ethnicity among older adults with radiographic knee osteoarthritis (n = 656 for cross-sectional analyses and n = 434 for longitudinal analyses). The data came from the Johnston County Osteoarthritis Project, a prospective cohort study in North Carolina designed to examine risk factors for osteoarthritis.

resultsAlthough few longitudinal associations were found, cross-sectional results suggested that greater perceived neighborhood social cohesion (B = -0.04, P < 0.001) and perceived neighborhood resources for physical activity and walking (B = -0.03, P < 0.001) were associated with fewer depressive symptoms, and that greater perceived neighborhood resources for physical activity and walking were associated with higher (better) knee impact scores (B = 0.48, P = 0.008). We also observed 2 significant interactions among neighborhood characteristics and race/ethnicity related to depressive symptoms (P < 0.01); for African American adults, greater perceived neighborhood resources for physical activity and walking were associated with fewer depressive symptoms (B = -0.03, P < 0.001), but for White adults, greater perceived neighborhood safety was associated with fewer depressive symptoms (B = -0.04, P = 0.003).

conclusionIn a sample of older adults with radiographic knee osteoarthritis, neighborhood context mattered, but in nuanced ways. Interventions aiming to improve mental and physical functioning of older adults with knee osteoarthritis can look to this study as evidence for the importance of neighborhood characteristics.

Indexed as

Residence CharacteristicsSocial Determinants of HealthSocioeconomic FactorsAgedAge FactorsBlack or African AmericanCooperative BehaviorCross-Sectional StudiesDepressionFemaleFunctional StatusHumansLongitudinal StudiesMaleMental HealthMiddle Aged

Identifiers

PMID31841258
PMCPMC7295685

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.