Evidence map›Paper›PMID 31840992›Full record

ArticleJournal of the American Chemical Society2019

Chemoenzymatic

Tyler J Doyon, Jonathan C Perkins, Summer A Baker Dockrey, Evan O Romero, Kevin C Skinner, Paul M Zimmerman, Alison R H Narayan

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Review
  3. Recent Breakthroughs in Cyclizations ofMolecules (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Enzymatic Peroxidation in the Chemoenzymatic Synthesis of 13-Oxoverruculogen.Synlett : accounts and rapid communications in synthetic organic chemistry · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Chemoenzymatic Synthesis of 13-Oxoverruculogen.Journal of the American Chemical Society · 2023
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. HarnessingJournal of natural products · 2022
    Review
  18. Article
  19. Engineered and Artificial Metalloenzymes for Selective C-H Functionalization.Current opinion in green and sustainable chemistry · 2021
    Article
  20. State-of-the-Art Biocatalysis.ACS central science · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tyler J Doyon
Jonathan C Perkins
Summer A Baker Dockrey
Evan O Romero
Kevin C Skinner
Alison R H NarayanORCID 0000-0001-8290-0077
University of Michigan · US

Funding

MICHIGAN CHEMISTRY-BIOLOGY INTERFACE TRAINING PROGRAMT32GM008597 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MONTGOMERY, JOHN · 1996 to 2018
$5.0M
Mechanism-Guided Catalyst Development through Reaction Discovery Simulation - Equipment SupplementR35GM128830 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZIMMERMAN, PAUL · 2018 to 2022
$1.9M
NIGMS NIH HHS R35 GM128830NIGMS NIH HHS T32 GM008597
6 · The paper itself

Abstract

Generation of reactive intermediates and interception of these fleeting species under physiological conditions is a common strategy employed by Nature to build molecular complexity. However, selective formation of these species under mild conditions using classical synthetic techniques is an outstanding challenge. Here, we demonstrate the utility of biocatalysis in generating

Indexed as

IndolequinonesMolecular StructureMonascusNonheme Iron ProteinsPenicilliumStereoisomerismIndolequinonesNonheme Iron Proteinsquinone methide

Identifiers

PMID31840992
PMCPMC7193901
OpenAlexW2994806319

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.