Evidence map›Paper›PMID 31840630›Full record

ArticleParasitology2020

João Vitor Barbosa Dos Santos, Douglas Siqueira de Almeida Chaves, Marco André Alves de Souza, Cristiano Jorge Riger, Monique Moraes Lambert, Diefrey Ribeiro Campos, Leandra Oliveira Moreira, Rosiane Conceição Dos Santos Siqueira, Rodrigo de Paulo Osorio, Fabio Boylan and 3 more

Abstract read
In one paragraph

Article in Parasitology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Potential ectoparasiticide for dog and cat fleas, a combination ofJournal of advanced veterinary and animal research · 2024
    Article
  5. Article
  6. Phytochemicals ofMolecules (Basel, Switzerland) · 2024
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

João Vitor Barbosa Dos SantosPharmaceutical Sciences Department, Health and Biological Science Institute, Federal Rural University of Rio de Janeiro, Seropédica, RJ, Brazil.
Douglas Siqueira de Almeida ChavesPharmaceutical Sciences Department, Health and Biological Science Institute, Federal Rural University of Rio de Janeiro, Seropédica, RJ, Brazil.
Marco André Alves de SouzaBiochemistry Department, Chemistry Institute, Federal Rural University of Rio de Janeiro, Seropédica, RJ, Brazil.
Cristiano Jorge RigerBiochemistry Department, Chemistry Institute, Federal Rural University of Rio de Janeiro, Seropédica, RJ, Brazil.
Monique Moraes LambertAnimal Parasitology Department, Veterinary Institute, Federal Rural University of Rio de Janeiro, Seropédica, RJ, Brazil.
Diefrey Ribeiro CamposAnimal Parasitology Department, Veterinary Institute, Federal Rural University of Rio de Janeiro, Seropédica, RJ, Brazil.
Leandra Oliveira MoreiraAnimal Parasitology Department, Veterinary Institute, Federal Rural University of Rio de Janeiro, Seropédica, RJ, Brazil.
Rosiane Conceição Dos Santos SiqueiraBiochemistry Department, Chemistry Institute, Federal Rural University of Rio de Janeiro, Seropédica, RJ, Brazil.
Rodrigo de Paulo OsorioBiochemistry Department, Chemistry Institute, Federal Rural University of Rio de Janeiro, Seropédica, RJ, Brazil.
Fabio BoylanSchool of Pharmacy and Pharmaceutical Sciences and Trinity Biosciences Medical Institute, Trinity College Dublin, Dublin, Ireland.
Thaís Ribeiro CorreiaSchool of Pharmacy and Pharmaceutical Sciences and Trinity Biosciences Medical Institute, Trinity College Dublin, Dublin, Ireland.
Katherina CoumendourosSchool of Pharmacy and Pharmaceutical Sciences and Trinity Biosciences Medical Institute, Trinity College Dublin, Dublin, Ireland.
Yara Peluso CidPharmaceutical Sciences Department, Health and Biological Science Institute, Federal Rural University of Rio de Janeiro, Seropédica, RJ, Brazil.ORCID 0000-0003-0775-0704

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Essential oils (EOs) are considered a new class of ecological products aimed at the control of insects for industrial and domestic use; however, there still is a lack of studies involving the control of fleas. Ctenocephalides felis felis, the most observed parasite in dogs and cats, is associated with several diseases. The aim of this study was to evaluate the in vitro activity, the establishment of LC50 and toxicity of EOs from Alpinia zerumbet (Pers.) B. L. Burtt & R. M. Sm, Cinnamomum spp., Laurus nobilis L., Mentha spicata L., Ocimum gratissimum L. and Cymbopogon nardus (L.) Rendle against immature stages and adults of C. felis felis. Bioassay results suggest that the method of evaluation was able to perform a pre-screening of the activity of several EOs, including the discriminatory evaluation of flea stages by their LC50. Ocimum gratissimum EO was the most effective in the in vitro assays against all flea stages, presenting adulticide (LC50 = 5.85 μg cm-2), ovicidal (LC50 = 1.79 μg cm-2) and larvicidal (LC50 = 1.21 μg cm-2) mortality at low doses. It also presented an excellent profile in a toxicological eukaryotic model. These findings may support studies involving the development of non-toxic products for the control of fleas in dogs and cats.

Indexed as

CtenocephalidesInsect ControlInsecticidesOils, VolatileAlpiniaAnimalsCinnamomumCymbopogonIn Vitro TechniquesLarvaLaurusMentha spicataOcimumOvumInsecticidesOils, VolatileEssential oilsfleasmortalitypets

Identifiers

PMID31840630
PMCPMC10317638

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.