Evidence map›Paper›PMID 31840442›Full record

ArticleJournal of biomedical optics2019

Quantitative phase and polarization imaging through an optical fiber applied to detection of early esophageal tumorigenesis.

George S D Gordon, James Joseph, Maria P Alcolea, Travis Sawyer, Calum Williams, Catherine R M Fitzpatrick, Philip H Jones, Massimiliano di Pietro, Rebecca C Fitzgerald, Timothy D Wilkinson and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of biomedical optics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Chiral phase-imaging meta-sensors.Nanophotonics (Berlin, Germany) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

George S D GordonUniversity of Cambridge, Department of Engineering, Cambridge, United Kingdom.
James JosephUniversity of Cambridge, Department of Physics, Cavendish Laboratory, Cambridge, United Kingdom.
Maria P AlcoleaUniversity of Cambridge, Wellcome Trust MRC Stem Cell Institute, Cambridge, United Kingdom.
Travis SawyerUniversity of Cambridge, Department of Physics, Cavendish Laboratory, Cambridge, United Kingdom.
Calum WilliamsUniversity of Cambridge, Department of Engineering, Cambridge, United Kingdom.
Catherine R M FitzpatrickUniversity of Cambridge, Department of Engineering, Cambridge, United Kingdom.
Philip H JonesUniversity of Cambridge, MRC Cancer Unit, Hutchison/MRC Research Centre, Cambridge, United Kingdom.
Massimiliano di PietroUniversity of Cambridge, MRC Cancer Unit, Hutchison/MRC Research Centre, Cambridge, United Kingdom.
Rebecca C FitzgeraldUniversity of Cambridge, MRC Cancer Unit, Hutchison/MRC Research Centre, Cambridge, United Kingdom.
Timothy D WilkinsonUniversity of Cambridge, Department of Engineering, Cambridge, United Kingdom.
Sarah E BohndiekUniversity of Cambridge, Department of Physics, Cavendish Laboratory, Cambridge, United Kingdom.
University of Cambridge · GBHutchison/MRC Research Centre · GBMRC Cancer Unit · GBWellcome Trust · GB

Funding

Cancer Research UK 16267Cancer Research UK 17257Cancer Research UK 21102Cancer Research UK 21142Cancer Research UK 24669Medical Research Council MC_PC_12009
6 · The paper itself

Abstract

Phase and polarization of coherent light are highly perturbed by interaction with microstructural changes in premalignant tissue, holding promise for label-free detection of early tumors in endoscopically accessible tissues such as the gastrointestinal tract. Flexible optical multicore fiber (MCF) bundles used in conventional diagnostic endoscopy and endomicroscopy scramble phase and polarization, restricting clinicians instead to low-contrast amplitude-only imaging. We apply a transmission matrix characterization approach to produce full-field

Indexed as

Optical FibersAlgorithmsAnimalsEsophageal NeoplasmsEsophagusFemaleImage Interpretation, Computer-AssistedMaleMiceMice, Inbred C57BLOptical ImagingPhantoms, Imagingcanceroptical fiberspolarimetryquantitative phase imaging

Identifiers

PMID31840442
PMCPMC7006047
OpenAlexW2900070567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.