Evidence map›Paper›PMID 31840197›Full record

ArticleFolia microbiologica2020

Antifungal xanthones produced by the endophytic fungus Paraconionthyrium sp. YM 311593.

Cuiping Miao, Junfei Wang, Rong Huang, Sisi Liu, Kaixuan Zheng, Chuansheng Liu, Yihan Lu, Shaohua Wu

Abstract read
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In one paragraph

Article in Folia microbiologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cuiping MiaoYunnan Institute of Microbiology, School of Life Sciences, Yunnan University, Kunming, 650091, China.
Junfei WangYunnan Institute of Microbiology, School of Life Sciences, Yunnan University, Kunming, 650091, China.
Rong HuangSchool of Chemical Science and Technology, Yunnan University, Kunming, 650091, China.
Sisi LiuYunnan Institute of Microbiology, School of Life Sciences, Yunnan University, Kunming, 650091, China.
Kaixuan ZhengYunnan Institute of Microbiology, School of Life Sciences, Yunnan University, Kunming, 650091, China.
Chuansheng LiuYunnan Institute of Microbiology, School of Life Sciences, Yunnan University, Kunming, 650091, China.
Yihan LuYunnan Institute of Microbiology, School of Life Sciences, Yunnan University, Kunming, 650091, China.
Shaohua WuYunnan Institute of Microbiology, School of Life Sciences, Yunnan University, Kunming, 650091, China. shwu123@126.com.ORCID http://orcid.org/0000-0003-4972-7449

Funding

National Natural Science Foundation of China 31660004National Natural Science Foundation of China 81860634, 81460545
6 · The paper itself

Abstract

During our investigation on the endophytic fungi of Azadirachta indica, the strain YM 311593 was obtained from the fruit of the plant. The culture extract of the strain showed antifungal activities against four phytopathogenic fungi. Based on the morphological features and phylogenetic definition, the strain YM 311593 was identified as Paraconiothyrium sp. Four xanthones and one anthraquinone were obtained from the extract of the fermentation broth of the strain. They were characterized to be globosuxanthone A (1), vertixanthone (2), hydroxyvertixanthone (3), 3,8-dihydroxy-1-methy1-9H- xanthen-9-one (4), and danthron (5), respectively, by spectroscopic elucidation. Furthermore, the absolute configuration of 1 was deduced by X-ray diffraction analysis. Besides, compound 4 was firstly found from natural sources. The antifungal activities of compounds 1-5 towards four phytopathogens were assayed using broth microdilution method. Among them, globosuxanthone A (1) showed obvious antifungal activity towards Fusarium graminearum, Fusarium solani, and Botrytis cinerea with MIC values of 4, 8, and 16 μg/mL, respectively.

Indexed as

AscomycotaAzadirachtaCulture MediaEndophytesFruitFungiFungicides, IndustrialPhylogenyXanthonesCulture MediaFungicides, IndustrialXanthonesAntifungal activityEndophytic fungiParaconionthyriumXanthones

Identifiers

PMID31840197

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