Evidence map›Paper›PMID 31840109›Full record

ArticleCommunications biology2019

T cell fate following

Sung-Moo Park, Tatsushi Omatsu, Yun Zhao, Naohiro Yoshida, Pankaj Shah, Rachid Zagani, Hans-Christian Reinecker

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. iScience · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Genomic Distribution of Pro-VirulentInternational journal of molecular sciences · 2023
    Article
  6. Article
  7. Modulation of cGAS-STING signaling by PPARα in a mouse model of ischemia-induced retinopathy.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sung-Moo Park *Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114 USA.ORCID 0000-0002-7505-1617
Tatsushi Omatsu *Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114 USA.ORCID 0000-0001-9823-5809
Yun ZhaoGastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114 USA.
Naohiro YoshidaGastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114 USA.ORCID 0000-0002-0974-4263
Pankaj ShahGastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114 USA.
Rachid ZaganiGastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114 USA.
Hans-Christian ReineckerGastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114 USA.ORCID 0000-0001-8283-644X
Harvard University · US

Funding

Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1991 to 2026
$35.3M
Innate Immune Defense Mechanisms in the IntestineR01AI113333 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI REINECKER, HANS-CHRISTIAN · 2014 to 2025
$5.7M
Antigen Recognition at Intestinal Epithelial InterphasesR01DK068181 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI REINECKER, HANS-CHRISTIAN · 2005 to 2017
$5.2M
NIAID NIH HHS R01 AI113333NIDDK NIH HHS P30 DK043351NIDDK NIH HHS R01 DK068181
6 · The paper itself

Abstract

The innate immune response following infection with entero-invasive bacterial species is triggered upon release of cyclic di-guanylate monophosphate (c-di-GMP) into the host cell cytosol. Bacterial c-di-GMP activates the intracellular Sensor Stimulator of Interferon Genes (STING), encoded by

Indexed as

Signal TransductionAnimalsAntigen PresentationDendritic CellsGene Expression ProfilingHost-Pathogen InteractionsImmunity, MucosalInterferon Regulatory Factor-1Lymphocyte ActivationMembrane ProteinsMicePhosphorylationSalmonellaSalmonella InfectionsSTING ProteinT-LymphocytesInterferon Regulatory Factor-1Irf1 protein, mouseMembrane ProteinsSting1 protein, mouseSTING ProteinAntigen processing and presentationMucosal immunologyPathogens

Identifiers

PMID31840109
PMCPMC6906324
OpenAlexW2996422619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.