ArticleCommunications biology2019
The vertebrate Aqp14 water channel is a neuropeptide-regulated polytransporter.
Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- Genome-wide identification and solute selectivity of aquaporins in the sharpnose sevengill shark, Heptranchias perlo.Physiological reports · 2026Article
- Targeting TNF/IL-17/MAPK pathway in hHaematologica · 2024Article
- slc26a12-A novel member of the slc26 family, is located in tandem with slc26a2 in coelacanths, amphibians, reptiles, and birds.Physiological reports · 2024Article
- Functional Divergence in Solute Permeability between Ray-Finned Fish-Specific Paralogs of aqp10.Genome biology and evolution · 2024Article
- Functional Evolution of Clustered Aquaporin Genes Reveals Insights into the Oceanic Success of Teleost Eggs.Molecular biology and evolution · 2023Article
- Boric acid transport activity of marine teleost aquaporins expressed in Xenopus oocytes.Physiological reports · 2023Article
- Neurohypophysial and paracrine vasopressinergic signaling regulates aquaporin trafficking to hydrate marine teleost oocytes.Frontiers in endocrinology · 2023Article
- Diversification of the aquaporin family in geographical isolated oyster species promote the adaptability to dynamic environments.BMC genomics · 2022Article
- Signaling Mechanisms and Pharmacological Modulators Governing Diverse Aquaporin Functions in Human Health and Disease.International journal of molecular sciences · 2022Review
- Lineage-level divergence of copepod glycerol transporters and the emergence of isoform-specific trafficking regulation.Communications biology · 2021Article
- Characteristics of aquaporin 1, 3, and 5 expression during early murine salivary gland development.Journal of anatomy · 2021Article
- Targeting Aquaporins in Novel Therapies for Male and Female Breast and Reproductive Cancers.Cells · 2021Review
- Polyploidization and pseudogenization in allotetraploid frog Xenopus laevis promote the evolution of aquaporin family in higher vertebrates.BMC genomics · 2020Article
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Water channels (aquaporins) were originally discovered in mammals with fourteen subfamilies now identified (AQP0-13). Here we show that a functional Aqp14 subfamily phylogenetically related to AQP4-type channels exists in all vertebrate lineages except hagfishes and eutherian mammals. In contrast to the water-selective classical aquaporins, which have four aromatic-arginine constriction residues, Aqp14 proteins present five non-aromatic constriction residues and facilitate the permeation of water, urea, ammonia, H
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