Evidence map›Paper›PMID 31840083›Full record

ArticleMed one2019

Transient versus Permanent MCA Occlusion in Mice Genetically Modified to Have Good versus Poor Collaterals.

Hua Zhang, James E Faber

Open access · diamondAbstract read
In one paragraph

Article in Med one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Stroke · 2025
    Article
  3. Article
  4. Review
  5. Large differences in collateral blood vessel abundance among individuals arise from multiple genetic variants.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hua ZhangDepartment of Cell Biology and Physiology, Curriculum in Neuroscience, McAllister Heart Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
James E FaberDepartment of Cell Biology and Physiology, Curriculum in Neuroscience, McAllister Heart Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
University of North Carolina at Chapel Hill · US

Funding

Targeting the Pial Collateral Circulation for Mitigation of Cerebral IschemiaR01NS083633 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ZHANG, HUA · 2013 to 2023
$4.5M
NINDS NIH HHS R01 NS083633
6 · The paper itself

Abstract

Collateral-dependent blood flow is capable of significantly lessening the severity of stroke. Unfortunately, collateral flow varies widely in patients for reasons that remain unclear. Studies in mice have shown that the number and diameter of cerebral collaterals vary widely due primarily to polymorphisms in genes, e.g.,

Indexed as

collateralsischemic strokeMCA ligationpermanenttransient

Identifiers

PMID31840083
PMCPMC6910253
OpenAlexW2990988087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.