Evidence map›Paper›PMID 31840044›Full record

ReviewNPJ Parkinson's disease2019

Report from a multidisciplinary meeting on anxiety as a non-motor manifestation of Parkinson's disease.

Gregory M Pontone, Nadeeka Dissanayka, Liana Apostolova, Richard G Brown, Roseanne Dobkin, Kathy Dujardin, Joseph H Friedman, Albert F G Leentjens, Eric J Lenze, Laura Marsh and 8 more

Erratum issuedAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in NPJ Parkinson's disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Management of Anxiety in Parkinson's Disease.Movement disorders clinical practice · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Cognitive Behavioral Therapy for Anxiety in Parkinson's Disease: A Randomized Controlled Trial.Movement disorders : official journal of the Movement Disorder Society · 2021
    Trial
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  6. Review
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  14. Review
  15. Article
  16. Basal ganglia theta power indexes trait anxiety in people with Parkinson's disease.medRxiv : the preprint server for health sciences · 2024
    Article
  17. Article
  18. Anxiety Change After Dopamine Therapy in Parkinson Disease is Independent of Motor Improvement.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2024
    Article
  19. Article
  20. Predictors of anxiety in Parkinson's disease: results from a 3-year longitudinal cohort study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Gregory M Pontone1Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD USA.ORCID 0000-0002-9540-6913
Nadeeka Dissanayka3The University of Queensland Centre for Clinical Research, Faculty of Medicine, Brisbane, Australia.
Liana Apostolova6Department of Neurology, Indiana University School of Medicine, Indianapolis, IN USA.
Richard G Brown7Department of Psychology, Institute of Psychiatry Psychology and Neuroscience, King's College London, London, UK.
Roseanne Dobkin9Department of Psychiatry, Rutgers University, Robert Wood Johnson Medical School, Piscataway, NJ USA.
Kathy Dujardin10Department of Neurology and Movement Disorders, Lille University Medical Center, Lille, France.ORCID 0000-0002-0110-574X
Joseph H Friedman11Movement Disorders Program, Butler Hospital; Department of Neurology, Warren Alpert Medical School of Brown University, Providence, RI USA.
Albert F G Leentjens12Department of Psychiatry, Maastricht University Medical Center, Maastricht, the Netherlands.
Eric J Lenze13Department of Psychiatry, Washington University School of Medicine, St. Louis, MO USA.
Laura Marsh14Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX USA.
Lynda MariPerson Holistic Innovation, Las Vegas, NV USA.
Oury Monchi17Departments of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, Canada.
Irene H Richard18Department of Neurology, University of Rochester Medical Center, Rochester, NY USA.
Anette Schrag19Department of Clinical and Movement Neurosciences, University College London, London, UK.ORCID 0000-0002-9872-6680
Antonio P Strafella20E.J. Safra Parkinson Disease Program, Toronto Western Hospital & Krembil Research Institute, UHN; Research Imaging Centre, Campbell Family Mental Health Research Institute, CAMH; University of Toronto, Ontario, Canada.
Beth VernaleoParkinson's Foundation, New York, NY USA.
Daniel Weintraub22Departments of Psychiatry and Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA USA.
Zoltan Mari24Cleveland Clinic Lou Ruvo Center for Brain Health, Movement Disorders Program, Las Vegas, NV USA.

Funding

Anxiety in Parkinson's: Use of quantitative methods to guide rational treatmentK23AG044441 · NIA · JOHNS HOPKINS UNIVERSITY · PI PONTONE, GREGORY MICHAEL · 2014 to 2018
$1.0M
NIA NIH HHS K23 AG044441
6 · The paper itself

Abstract

Anxiety is a severe problem for at least one-third of people living with Parkinson's disease (PD). Anxiety appears to have a greater adverse impact on quality of life than motor impairment. Despite its high prevalence and impact on daily life, anxiety is often undiagnosed and untreated. To better address anxiety in PD, future research must improve knowledge about the mechanism of anxiety in PD and address the lack of empirical evidence from clinical trials. In response to these challenges, the Parkinson's Foundation sponsored an expert meeting on anxiety on June 13th and 14th 2018. This paper summarizes the findings from that meeting informed by a review of the existing literature and discussions among patients, caregivers, and an international, clinician-scientist, expert panel working group. The goal is to provide recommendations to improve our understanding and treatment of anxiety in PD.

Indexed as

Parkinson's disease

Identifiers

PMID31840044
PMCPMC6906437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.