Evidence map›Paper›PMID 31840007›Full record

ArticleACS catalysis2019

Evidence for a Catalytic Strategy to Promote Nucleophile Activation in Metal-Dependent RNA-Cleaving Ribozymes and 8-17 DNAzyme.

Abir Ganguly, Benjamin P Weissman, Joseph A Piccirilli, Darrin M York

Open access · bronzeAbstract read
In one paragraph

Article in ACS catalysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Surface-Accelerated String Method for Locating Minimum Free Energy Paths.Journal of chemical theory and computation · 2024
    Article
  3. Article
  4. Article
  5. Organic & biomolecular chemistry · 2022
    Article
  6. Investigation of the pThe journal of physical chemistry. B · 2021
    Article
  7. Article
  8. Synthesis of Oligoribonucleotides Containing a 2'-Amino-5'-The Journal of organic chemistry · 2021
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Abir GangulyLaboratory for Biomolecular Simulation Research, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854-8087, United States.
Benjamin P WeissmanDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.
Joseph A PiccirilliDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.
Darrin M YorkLaboratory for Biomolecular Simulation Research, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854-8087, United States.
Rutgers, The State University of New Jersey · USUniversity of Chicago · US

Funding

Multi-Scale Quantum Models for Ribozyme CatalysisR01GM062248 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Darrin M York · 2001 to 2026
$7.1M
Predoctoral Training Program in Chemistry & BiologyT32GM008720 · NIGMS · UNIVERSITY OF CHICAGO · PI PICCIRILLI, JOSEPH ANTHONY · 1999 to 2020
$4.7M
Supercomputing: Rutgers' Catalyst for Discovery at the Frontiers of MedicineS10OD012346 · OD · RBHS-NEW JERSEY MEDICAL SCHOOL · PI MICHELSON, LESLIE PAUL · 2015 to 2015
$1.7M
The VS Ribozyme: Catalytic Mechanism, Transition State Structure, and EvolutionR01GM131568 · NIGMS · UNIVERSITY OF CHICAGO · PI PICCIRILLI, JOSEPH ANTHONY · 2019 to 2022
$1.4M
NIGMS NIH HHS R01 GM062248NIGMS NIH HHS R01 GM131568NIGMS NIH HHS T32 GM008720NIH HHS S10 OD012346
6 · The paper itself

Abstract

An unique catalytic strategy was recently reported for the

Identifiers

PMID31840007
PMCPMC6902279
OpenAlexW2981702730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.