ArticleMultiple sclerosis journal - experimental, translational and clinical
High serum concentration of vitamin D may protect against multiple sclerosis.
Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Seropositivity against rubella virus envelope protein 1, but not 2, is associated with an increased risk of multiple sclerosis.Clinical & translational immunology · 2026Article
- Human herpesvirus 7 and the risk of developing multiple sclerosis.Brain communications · 2026Article
- Potential pathogenic and protective genotypes and phenotypes of vitamin D binding protein in multiple sclerosis.Frontiers in neurology · 2025Article
- Rubella virus seropositivity after infection or vaccination as a risk factor for multiple sclerosis.European journal of neurology · 2024Article
- Seroreactivity against lytic, latent and possible cross-reactive EBV antigens appears on average 10 years before MS induced preclinical neuroaxonal damage.Journal of neurology, neurosurgery, and psychiatry · 2024Article
- Human herpesvirus 6A and axonal injury before the clinical onset of multiple sclerosis.Brain : a journal of neurology · 2024Article
- Free vitamin DEuropean journal of neurology · 2022Article
- Axonal injury in asymptomatic individuals preceding onset of multiple sclerosis.Annals of clinical and translational neurology · 2022Article
- Uptake of Vitamins DNutrients · 2021Article
- Does the High Prevalence of Vitamin D Deficiency in African Americans Contribute to Health Disparities?Nutrients · 2021Review
- The Multiple Sclerosis Prodrome: Evidence to Action.Frontiers in neurology · 2021Article
- Systemic inflammation and risk of multiple sclerosis - A presymptomatic case-control study.Multiple sclerosis journal - experimental, translational and clinicalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHigh 25-hydroxyvitamin D concentrations have been associated with a reduced risk of multiple sclerosis, with indications of a stronger effect among young individuals.
objectiveInvestigate the 25-hydroxyvitamin D association with multiple sclerosis and test if this association is age dependent.
methodsProspectively drawn blood samples from individuals later developing relapsing-remitting multiple sclerosis and controls matched for biobank, sex, age and date of sampling, were analysed with liquid chromatography tandem mass spectrometry.
resultsHigh levels of 25-hydroxyvitamin D (top quintile) were associated with a reduced multiple sclerosis risk (odds ratio 0.68, 95% confidence interval 0.50-0.93).
conclusionThese findings further support a role for vitamin D in MS aetiology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.