Evidence map›Paper›PMID 31839956›Full record

ArticleUnited European gastroenterology journal2019

Mean muscle attenuation correlates with severe acute pancreatitis unlike visceral adipose tissue and subcutaneous adipose tissue.

Hanna Sternby, Mariella Mahle, Nicolas Linder, Laureen Erichson-Kirst, Robert C Verdonk, Alexandra Dimova, Povilas Ignatavicius, Lucas Ilzarbe, Peeter Koiva, Anne Penttilä and 10 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in United European gastroenterology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  8. Review
  9. Clinical and imaging predictors for the development of diabetes mellitus following a single episode of acute pancreatitis in youth.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2025
    Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Predicting Severity of Acute Pancreatitis.Medicina (Kaunas, Lithuania) · 2022
    Review
  16. Article
  17. UEGWeek: The modern School of Athens.United European gastroenterology journal · 2021
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 10 institutions in 9 countries.

Hanna SternbyDepartment of Surgery, Institution of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Mariella MahleDepartment of Internal Medicine I, Martin Luther University, Halle (Saale), Germany.
Nicolas LinderDepartment of Diagnostic and Interventional Radiology, University Hospital Leipzig, Leipzig, Germany.
Laureen Erichson-KirstDepartment of Internal Medicine, Neurology and Dermatology, Division of Gastroenterology, Leipzig, Germany.
Robert C VerdonkDepartment of Gastroenterology, St. Antonius Ziekenhuis, Nieuwegein, the Netherlands.
Alexandra DimovaDepartment of Surgery, University Hospital for Emergency Medicine "Pirogov", Sofia, Bulgaria.
Povilas IgnataviciusDepartment of Surgery, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Lucas IlzarbeDepartment of Gastroenterology, Hospital del Mar, Barcelona, Spain.
Peeter KoivaDepartment of Gastroenterology, East Tallinn Central Hospital, Tallinn, Estonia.
Anne PenttiläDepartment of Surgery, Helsinki University Central Hospital, Helsinki, Finland.
Sara RegnérDepartment of Surgery, Institution of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Thomas L BollenDepartment of Radiology, St. Antonius Ziekenhuis, Nieuwegein, the Netherlands.
Richard BrillDepartment of Radiology, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Franz StanglDepartment of Radiology, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Walter A WohlgemuthDepartment of Radiology, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
Vijay SinghDepartment of Medicine, Mayo Clinic, Scottsdale, Arizona, USA.
Harald BusseDepartment of Diagnostic and Interventional Radiology, University Hospital Leipzig, Leipzig, Germany.
Patrick MichlDepartment of Internal Medicine I, Martin Luther University, Halle (Saale), Germany.
Sebastian BeerDepartment of Internal Medicine, Neurology and Dermatology, Division of Gastroenterology, Leipzig, Germany.
Jonas RosendahlDepartment of Internal Medicine I, Martin Luther University, Halle (Saale), Germany.
Martin Luther University Halle-Wittenberg · DEUniversity Hospital Leipzig · DEMalmö University · SESt. Antonius Ziekenhuis · NLEast Tallinn Central Hospital · EEHelsinki University Hospital · FIHospital Del Mar · ESLithuanian University of Health Sciences · LTMayo Clinic in Arizona · USNational Institute of Emergency Medicine "Pirogov" · BG

Funding

Obesity related pancreatic fat worsens local injury via unsaturated fatty acidsR01DK092460 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SINGH, VIJAY PREM · 2011 to 2024
$5.5M
NIDDK NIH HHS R01 DK092460
6 · The paper itself

Abstract

Background: Acute pancreatitis (AP) is a frequent disorder with considerable morbidity and mortality. Obesity has previously been reported to influence disease severity. Objective: The aim of this study was to investigate the association of adipose and muscle parameters with the severity grade of AP. Methods: In total 454 patients were recruited. The first contrast-enhanced computed tomography of each patient was reviewed for adipose and muscle tissue parameters at L3 level. Associations with disease severity were analysed through logistic regression analysis. The predictive capacity of the parameters was investigated using receiver operating characteristic (ROC) curves. Results: No distinct variation was found between the AP severity groups in either adipose tissue parameters (visceral adipose tissue and subcutaneous adipose tissue) or visceral muscle ratio. However, muscle mass and mean muscle attenuation differed significantly with Conclusions: Our results demonstrate that a low muscle attenuation level is associated with an increased risk of severe AP. Future prospective studies will help identify the underlying mechanisms and characterise the influence of body composition parameters on AP.

Indexed as

AdultAgedBody CompositionFemaleHumansIntra-Abdominal FatMaleMiddle AgedMusclesOdds RatioPancreatitisRadiographic Image EnhancementROC CurveSeverity of Illness IndexSubcutaneous FatTomography, X-Ray ComputedAcute pancreatitismean muscle attenuationmuscle massseverityvisceral adipose tissue

Identifiers

PMID31839956
PMCPMC6893994
OpenAlexW2980051920

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.