Evidence map›Paper›PMID 31839864›Full record

ArticleThe Neurohospitalist2020

Clinical Spectrum of West Nile Virus Neuroinvasive Disease.

Andrew Yu, Emily Ferenczi, Kareem Moussa, Dean Eliott, Marcelo Matiello

Open access · bronzeAbstract read
In one paragraph

Article in The Neurohospitalist, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Rehabilitation approaches in West Nile Virus survivors: a systematic review.European journal of physical and rehabilitation medicine · 2024
    Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Neurology of Acute Viral Infections.The Neurohospitalist · 2022
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Andrew YuDepartment of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.ORCID https://orcid.org/0000-0003-3346-2407
Emily FerencziDepartment of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.
Kareem MoussaMassachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Dean EliottMassachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Marcelo MatielloDepartment of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.
Harvard University · USMassachusetts Eye and Ear Infirmary · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

West Nile virus (WNV) is the most common arbovirus infection in the United States. The diagnosis requires consideration of not only a broad spectrum of presenting symptoms, ranging from a mild febrile illness to severe encephalitis and acute flaccid paralysis, but also public health risk factors and seasonality. There is no approved targeted therapy for WNV, so treatment relies on supportive care, management of neurologic sequelae and airway, treatment of other systems including the eye, and aggressive rehabilitation. Here, we describe a series of 3 cases of WNV encountered in September 2018 at one institution. First, we describe a case of WNV encephalitis with worsened dyskinesias and a relatively good recovery. Second, we describe a severe WNV encephalitis with overlying motor neuron involvement with a poor outcome. Finally, we describe a case of a WNV meningitis with significant bilateral chorioretinitis, an underappreciated complication of WNV infections. Through these cases, we review the epidemiology of WNV, risk factors for infection, the neurologic sequalae and long-term outcomes, and the importance of recognizing ocular involvement to prevent ophthalmologic complications.

Indexed as

chorioretinitisencephalitismeningitisWest Nile virus

Identifiers

PMID31839864
PMCPMC6900655
OpenAlexW2967479384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.