Evidence map›Paper›PMID 31839780›Full record

ArticlePostepy dermatologii i alergologii2019

Evaluation of periostin level for predicting severity and chronicity of childhood atopic dermatitis.

Deniz Ozceker, Esra Yucel, Sevgi Sipahi, Fatih Dilek, Emin Ozkaya, Eray Metin Guler, Abdurrahim Kocyigit, Nermin Guler, Zeynep Tamay

Open access · goldAbstract read
In one paragraph

Article in Postepy dermatologii i alergologii, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Deniz OzcekerDepartment of Pediatric Allergy and Immunology, Okmeydanı Education and Resarch Hospital, Saglik Bilimleri University, Istanbul, Turkey.
Esra YucelDepartment of Pediatric Allergy and Immunology, Okmeydanı Education and Resarch Hospital, Saglik Bilimleri University, Istanbul, Turkey.
Sevgi SipahiDepartment of Pediatric Allergy and Immunology, Istanbul Medical Faculty, Istanbul, Turkey.
Fatih DilekDepartment of Pediatric Allergy and Immunology, Bezmi Alem University, Medical Faculty, Istanbul, Turkey.
Emin OzkayaDepartment of Pediatric Allergy and Immunology, Bezmi Alem University, Medical Faculty, Istanbul, Turkey.
Eray Metin GulerDepartment of Biochemistry, Bezmi Alem University, Medical Faculty, Istanbul, Turkey.
Abdurrahim KocyigitDepartment of Biochemistry, Bezmi Alem University, Medical Faculty, Istanbul, Turkey.
Nermin GulerDepartment of Pediatric Allergy and Immunology, Istanbul Medical Faculty, Istanbul, Turkey.
Zeynep TamayDepartment of Pediatric Allergy and Immunology, Istanbul Medical Faculty, Istanbul, Turkey.
Bezmiâlem Vakıf Üniversitesi · TRIstanbul University · TRSağlık Bilimleri Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPeriostin has some effects on the pathogenesis of atopic dermatitis (AD) via release of pro-inflammatory cytokines and chemokines from activated keratinocytes and it is related to chronicity of skin lesions.

aimTo evaluate the relationship between plasma periostin levels and severity and chronicity of AD in children. MATERIAL AND

methodsThe study population consisted of 29 children with atopic dermatitis without concomitant allergic disease such as asthma or allergic rhinitis and 31 healthy controls. Data of demographic features, serum eosinophil, total IgE and skin prick test results were collected through the patient's medical records. The severity of the disease was assessed by the SCORAD index. Serum periostin levels were measured with a human periostin ELISA kit.

resultsThe mean ages of the AD patients and the control group participants were 80.7 ±52.8 and 90.3 ±41.6 months, respectively. Mean plasma periostin levels were 63.0 ±19.0 ng/ml in AD patients, and 23.6 ±7.3 in healthy controls, and there was a statistically significant difference between the two groups (

conclusionsThis study showed that plasma periostin levels were increased in children with atopic dermatitis. Periostin may have a partial role in the pathogenesis of atopic dermatitis, but it is not associated with severity or chronicity in children with atopic dermatitis.

Indexed as

atopic dermatitischildreneczemaperiostin

Identifiers

PMID31839780
PMCPMC6906968
OpenAlexW2907320870

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.