Evidence map›Paper›PMID 31839772›Full record

ArticlePostepy dermatologii i alergologii2019

Visfatin and chemerin levels correspond with inflammation and might reflect the bridge between metabolism, inflammation and fibrosis in patients with systemic sclerosis.

Karolina Sawicka, Małgorzata Michalska-Jakubus, Emilia Potembska, Małgorzata Kowal, Aldona Pietrzak, Dorota Krasowska

Open access · goldAbstract read
In one paragraph

Article in Postepy dermatologii i alergologii, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  11. Role of visfatin in obesity-induced insulin resistance.World journal of clinical cases · 2022
    Review
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  13. Review
  14. Article
  15. Article
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  17. Adipokines and Inflammation: Focus on Cardiovascular Diseases.International journal of molecular sciences · 2020
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Karolina SawickaDepartment of Dermatology, Venereology and Pediatric Dermatology, Medical University of Lublin, Lublin, Poland.
Małgorzata Michalska-JakubusDepartment of Dermatology, Venereology and Pediatric Dermatology, Medical University of Lublin, Lublin, Poland.
Emilia PotembskaDepartment of Psychiatric Nursing, Medical University of Lublin, Lublin, Poland.
Małgorzata KowalDepartment of Dermatology, Venereology and Pediatric Dermatology, Medical University of Lublin, Lublin, Poland.
Aldona PietrzakDepartment of Dermatology, Venereology and Pediatric Dermatology, Medical University of Lublin, Lublin, Poland.
Dorota KrasowskaDepartment of Dermatology, Venereology and Pediatric Dermatology, Medical University of Lublin, Lublin, Poland.
Medical University of Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAdipokines are regulatory molecules which act as mediators of the inflammatory, fibrotic and metabolic processes by interacting with the immune system.

aimWe hypothesized that chemerin and visfatin by pro-inflammatory properties play a significant role in inflammation in systemic sclerosis. To address this hypothesis, we determined serum chemerin and visfatin levels in SSc patients, compared with the control group and defined the correlations with clinical and laboratory parameters in SSc patients. MATERIAL AND

methodsThe study included 48 Caucasian female patients with SSc and 38 healthy subjects of the control group. Serum concentrations of selected adipokines were measured using commercially available ELISA Kits.

resultsPatients with SSc had higher chemerin levels (209.38 ±55.35 ng/ml) than the control group (182.71 ±33.94 ng/ml) and the difference was statistically significant (

conclusionsThe results of our study indicate that chemerin and visfatin as pro-inflammatory cytokines might represent new markers corresponding with inflammation in systemic sclerosis and might reflect the bridge between metabolism, inflammation and potentially, chemerin may also link inflammation with skin and lung fibrosis.

Indexed as

chemerinsystemic sclerosisvisfatin

Identifiers

PMID31839772
PMCPMC6906965
OpenAlexW2901991582

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.