Evidence map›Paper›PMID 31839708›Full record

ArticleJournal of multidisciplinary healthcare2019

Depressive Symptoms in Older versus Younger People with Epilepsy: Findings from an Integrated Epilepsy Self-Management Clinical Research Dataset.

Zaira Khalid, Hasina Momotaz, Farren Briggs, Kristin A Cassidy, Naomi S Chaytor, Robert T Fraser, Mary R Janevic, Barbara Jobst, Erica K Johnson, Peter Scal and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of multidisciplinary healthcare, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Modelling risk factors for depressive symptoms in seizure disorders.Therapeutic advances in neurological disorders · 2026
    Article
  2. Review
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zaira KhalidDepartment of Psychiatry, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center , Cleveland, OH, USA.
Hasina MomotazDepartment of Neurology, Case Western Reserve University School of Medicine, Neurological and Behavioral Outcomes Center, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.ORCID 0000-0002-3469-9935
Farren BriggsDepartment of Population Health and Quantitative Science, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.ORCID 0000-0003-0903-1359
Kristin A CassidyDepartment of Psychiatry, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center , Cleveland, OH, USA.ORCID 0000-0003-1407-816X
Naomi S ChaytorDepartment of Medical Education and Clinical Sciences, Elson S. Floyd College of Medicine, Washington State University, Spokane, WA, USA.ORCID 0000-0001-8821-289X
Robert T FraserDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA, USA.
Mary R JanevicCenter for Managing Chronic Disease, University of Michigan School of Public Health, Ann Arbor, MI, USA.ORCID 0000-0001-5782-4893
Barbara JobstDepartment of Neurology, Geisel School of Medicine at Dartmouth, Dartmouth College, Lebanon, NH, USA.
Erica K JohnsonHealth Promotion Research Center, University of Washington, Seattle, WA, USA.
Peter ScalDepartment of Pediatrics and Adolescent Health, University of Minnesota, Minneapolis, MN, USA.
Tanya M SpruillDepartment of Population Health, NYU School of Medicine, New York, NY, USA.
Betsy K WilsonDepartment of Neurology, Case Western Reserve University School of Medicine, Neurological and Behavioral Outcomes Center, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Martha SajatovicDepartment of Psychiatry, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center , Cleveland, OH, USA.

Funding

ACL HHS U48DP005008ACL HHS U48DP005013ACL HHS U48DP005018ACL HHS U48DP005030NCCDPHP CDC HHS U48 DP001930NCCDPHP CDC HHS U48 DP005013NCCDPHP CDC HHS U48 DP005030
6 · The paper itself

Abstract

aimThere are limited data on psychological outcomes in older people with epilepsy (PWE). This analysis, from a large pooled dataset of clinical studies from the Managing Epilepsy Well (MEW) Network, examined clinical variables including depressive symptom severity, quality of life and epilepsy self-management competency among older (age 55+) vs younger (<age 55) PWE. We were particularly interested in differences between older vs younger individuals with clinically significant depression.

methodsAnalyses used baseline data from 9 MEW Network studies and examined demographic and clinical variables. Older vs younger individuals were compared and then we assessed groups with clinically significant depression vs those without clinically significant depression using the PHQ-9 and QOLIE-10 as a measure of quality of life.

resultsThe sample included 935 individuals. Compared to younger adults (n=774), the older group (n=161) had a better quality of life (p= 0.041) and more individuals without clinically significant depression (p=0.038). There was a trend for slightly lower depression severity scores (PHQ-9 total) (p=0.07) in the older group and a trend for fewer seizures (p=0.055) in older adults relative to younger adults.

conclusionCompared to younger PWE, older PWE have less clinically significant depression and better quality of life. Future research needs to identify possible mechanisms underlying these differences.

Indexed as

databasedepressionepilepsyquality of lifeself-management

Identifiers

PMID31839708
PMCPMC6904884

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