Evidence map›Paper›PMID 31839663›Full record

ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2020

A Fluorescent Sensor Based on Reversible Addition-Fragmentation Chain Transfer Polymerization for the Early Diagnosis of Non-small Cell Lung Cancer.

Wenwen Liu, Ligang Ma, Zhuangzhuang Guo, Tao Liu, Yanju Liu, Dazhong Wang, Jinming Kong

Abstract read
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In one paragraph

Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Multiplex MicroRNA Detection on a Surface-Functionalized Power-Free Microfluidic Chip.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2021
    Article
  2. Sensors with Highly Ordered Nucleotides.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenwen LiuOutpatient Integrated Systems Division, People's Hospital of Zhengzhou, 33 Yellow River Road, Zhengzhou, 450053, China.
Ligang MaDepartment of Mathematical and Chemical, Pharmacy College, Henan University of Chinese Medicine, Zhengzhou, 450046, China.
Zhuangzhuang GuoDepartment of Mathematical and Chemical, Pharmacy College, Henan University of Chinese Medicine, Zhengzhou, 450046, China.
Tao LiuDepartment of Mathematical and Chemical, Pharmacy College, Henan University of Chinese Medicine, Zhengzhou, 450046, China.
Yanju LiuDepartment of Mathematical and Chemical, Pharmacy College, Henan University of Chinese Medicine, Zhengzhou, 450046, China. Liuyanju886@hactcm.edu.cn.
Dazhong WangOutpatient Integrated Systems Division, People's Hospital of Zhengzhou, 33 Yellow River Road, Zhengzhou, 450053, China. wdzlion_fox@163.com.
Jinming KongSchool of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, 210094, China. j.kong@njust.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We propose a novel, ultrasensitive and low-cost sensor using reversible addition-fragmentation chain transfer (RAFT) polymerization as a signal amplification strategy for the detection of CYFRA 21-1 DNA fragment, a tumor marker of non-small cell lung carcinoma. The peptide nucleic acid (PNA) probes were firstly immobilized on magnetic beads (MBs) to capture the CYFRA 21-1 DNA specifically. After hybridization, CPAD was tethered to the hetero duplexes through carboxylate-Zr

Indexed as

Early Detection of CancerAntigens, NeoplasmBiomarkers, TumorCarcinoma, Non-Small-Cell LungDNA, NeoplasmFluorescent DyesHumansKeratin-19Limit of DetectionLung NeoplasmsMolecular StructureNucleic Acid HybridizationPeptide Nucleic AcidsPolymerizationantigen CYFRA21.1Antigens, NeoplasmBiomarkers, TumorDNA, NeoplasmFluorescent DyesKeratin-19Peptide Nucleic AcidsCYFRA 21-1 DNAfluorescencenon-small cell lung carcinomasRAFT

Identifiers

PMID31839663

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.