ArticleEpidemiology and psychiatric sciences2019
Household economic burden and outcomes of patients with schizophrenia after being unlocked and treated in rural China.
Article in Epidemiology and psychiatric sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Examination on the Acceptability, Feasibility and Effectiveness of a Digital Cognitive Training Software in Patients With Stable Schizophrenia in China.Neuropsychiatric disease and treatment · 2025Trial
- Family caregivers' willingness to use online psychological therapy for individuals with mental illness in China: a cross-sectional study.Frontiers in public health · 2026Article
- Patient subgroups and shifting incidence trends: an epidemiological profile of registered severe mental disorders in Quzhou, China (1969-2022).Frontiers in public health · 2026Article
- Community management: An effective model to reduce medication discontinuation rate in patients with schizophrenia.PloS one · 2026Article
- Legal Protection of Mental Health for Family Caregivers of People with Mental Disorders: Challenges, Current Situation, and Legislative Response.Psychology research and behavior management · 2025Review
- Relationship between medication burden and medication experience in stable patients with schizophrenia: the mediating effect of medication belief.BMC nursing · 2024Article
- Cost-utility analysis of using paliperidone palmitate in schizophrenia in China.Frontiers in pharmacology · 2023Article
- Article
- Barriers to medication adherence for rural patients with mental disorders in eastern China: a qualitative study.BMC psychiatry · 2021Article
- Mortality and excess life-years lost in patients with schizophrenia under community care: a 5-year follow-up cohort study.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)Article
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Authors and funding
15 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsPatients with severe mental disorders in low-resource settings have limited access to services, resulting in overwhelming caregiving burden for families. In extreme cases, this has led to the long-term restraining of patients in their homes. China underwent a nationwide initiative to unlock patients and provide continued treatment. This study aims to quantify household economic burden in families after unlocking and treatment, and to identify factors associated with increased burden due to schizophrenia.
methodsA total of 264 subjects were enrolled from three geographically diverse provinces in 2012. Subjects were patients with schizophrenia who were previously put under restraints and had participated in the 'unlocking and treatment' intervention. The primary outcome was the current household economic burden, obtained from past year financial information collected through on-site interview. Patient disease characteristics, treatment, outcomes and family caregiving burden were collected as well. Univariate and multivariate linear regression were used to construct risk factor models for indirect economic burden.
resultsAfter participating in the intervention, 85% of patients continued to receive mental health services, 70% used medication as prescribed and 80% were never relocked. Family members reported significantly decreased caregiving burden after receiving the intervention. Mean direct and indirect household economic burdens were CNY963 (US$31.7) and CNY11 724 (US$1670) per year, respectively, while family total income was on average CNY12 108 (US$1913) per year. Greater disease severity and poorer patient psychosocial function at time of study were found to be independent factors related to increased indirect burden.
conclusionsThe 'unlocking and treatment' intervention has improved the lives of patients and families. Indirect burden due to disease is still a major economic issue that needs to be addressed, potentially through improving treatment and patient functioning. Our findings contribute to the unravelling and eventual elimination of chronic restraining of mentally ill patients in low-resource settings.
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