Evidence map›Paper›PMID 31838586›Full record

ReviewVirchows Archiv : an international journal of pathology2020

Molecular findings in maxillofacial bone tumours and its diagnostic value.

Arjen H G Cleven, Willem H Schreuder, Eline Groen, Herman M Kroon, Daniel Baumhoer

Open access · hybridAbstract readReview
In one paragraph

Review in Virchows Archiv : an international journal of pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Molecular Alterations in Osteosarcomas of the Oral and Maxillofacial Region: A Scoping Review.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Low-grade chondrosarcoma of the larynx: A case report.World journal of clinical cases · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Arjen H G ClevenDepartment of Pathology, Leiden University Medical Center, PO, Box 9600, L1-Q, 2300 RC, Leiden, the Netherlands. a.h.g.cleven@lumc.nl.
Willem H SchreuderDepartment of Oral and Maxillofacial Surgery/Head and Neck Surgery, Amsterdam University Medical Center/Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.
Eline GroenDepartment of Pathology, Leiden University Medical Center, PO, Box 9600, L1-Q, 2300 RC, Leiden, the Netherlands.
Herman M KroonDepartment of Radiology, Leiden University Medical Center, Leiden, the Netherlands.
Daniel BaumhoerBone Tumour Reference Centre, Institute of Pathology, University Hospital Basel, University of Basel, Basel, Switzerland.
Leiden University Medical Center · NLThe Netherlands Cancer Institute · NLUniversity Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the WHO, mesenchymal tumours of the maxillofacial bones are subdivided in benign and malignant maxillofacial bone and cartilage tumours, fibro-osseous and osteochondromatous lesions as well as giant cell lesions and bone cysts. The histology always needs to be evaluated considering also the clinical and radiological context which remains an important cornerstone in the classification of these lesions. Nevertheless, the diagnosis of maxillofacial bone tumours is often challenging for radiologists as well as pathologists, while an accurate diagnosis is essential for adequate clinical decision-making. The integration of new molecular markers in a multidisciplinary diagnostic approach may not only increase the diagnostic accuracy but potentially also identify new druggable targets for precision medicine. The current review provides an overview of the clinicopathological and molecular findings in maxillofacial bone tumours and discusses the diagnostic value of these genetic aberrations.

Indexed as

ChondrosarcomaFacial BonesFibrous Dysplasia of BoneGranuloma, Giant CellHumansMaxillary NeoplasmsSkull NeoplasmsFibro-osseous lesionsGenetic aberrationsMaxillofacial bone tumoursMultidisciplinary diagnostic approach

Identifiers

PMID31838586
PMCPMC6968989
OpenAlexW2994761709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.