Evidence map›Paper›PMID 31838571›Full record

Observational studyDiabetologia2020

A comparison of obesity indices in relation to mortality in type 2 diabetes: the Fremantle Diabetes Study.

Joel Tate, Matthew Knuiman, Wendy A Davis, Timothy M E Davis, David G Bruce

Open access · bronzeAbstract readComparative StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Diabetologia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

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  20. The obesity paradox and diabetes.Eating and weight disorders : EWD · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Joel TateSchool of Population and Global Health, University of Western Australia, Nedlands, WA, Australia.
Matthew KnuimanSchool of Population and Global Health, University of Western Australia, Nedlands, WA, Australia.
Wendy A DavisMedical School, Fremantle Hospital, PO Box 480, Fremantle, WA, 6959, Australia.
Timothy M E DavisMedical School, Fremantle Hospital, PO Box 480, Fremantle, WA, 6959, Australia.
David G BruceMedical School, Fremantle Hospital, PO Box 480, Fremantle, WA, 6959, Australia. david.bruce@uwa.edu.au.
Fremantle Hospital · AUUniversity of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aims/hypothesisThis prospective association study aimed to compare the relationship between each of four obesity indices and mortality risk in people with type 2 diabetes.

methodsThe associations of BMI, waist circumference, WHR and A Body Shape Index (ABSI) with all-cause mortality were analysed in 1282 participants of the Fremantle Diabetes Study, followed for up to 20 years after baseline assessment. Models were adjusted for age and other confounders; assessments as continuous measures and by quintile were carried out for men and women separately. Sensitivity analyses were conducted to minimise reverse causality.

resultsWhen indices were assessed as continuous variables, there were significant bivariate associations with mortality for: ABSI, which was greater in both men and women who died (p < 0.001); WHR, which was greater in women only (p = 0.033); and BMI, which was lower in women only (p < 0.001). When assessed by quintile, there were significant bivariate associations with mortality for ABSI in men and women (p < 0.001) and BMI in women only (p = 0.002). In Cox models of time to death, adjusted for age, diabetes duration, ethnicity and smoking, ABSI quintiles showed a linear trend for both men (p = 0.003) and women (p = 0.035). Men in the fifth ABSI quintile had an increased mortality risk compared with those in the first quintile (HR [95% CI]: 1.74 [1.24, 2.44]) and women in the fifth ABSI quintile had an increased mortality risk that approached statistical significance (1.42 [0.97, 2.08], p = 0.08). Men in the fifth WHR quintile had an increased mortality risk (1.47 [1.05, 2.06]). There was no association between mortality and BMI or waist circumference in either sex. CONCLUSIONS/

interpretationABSI was the obesity index most strongly associated with all-cause mortality in Australians with type 2 diabetes. There was no evidence for an obesity paradox with any of the assessed indices. ABSI may be a better index of central obesity than waist circumference, BMI or WHR when assessing mortality risk in type 2 diabetes.

Indexed as

Health Status IndicatorsAdiposityAgedBody Mass IndexCohort StudiesDiabetes Mellitus, Type 2FemaleHumansMaleMiddle AgedObesityRisk FactorsSomatotypesWaist CircumferenceWaist-Hip RatioWestern AustraliaA Body Shape IndexBody Mass IndexCohort studyLongitudinal studyMortalityObesity paradoxType 2 diabetesWaist CircumferenceWaist-Hip ratio

Identifiers

PMID31838571
OpenAlexW2995720888

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.