Evidence map›Paper›PMID 31837950›Full record

ArticleThe American journal of pathology2020

Collagen VI Deficiency Results in Structural Abnormalities in the Mouse Lung.

Jared A Mereness, Soumyaroop Bhattacharya, Yue Ren, Qian Wang, Christopher S Anderson, Kathy Donlon, Andrew M Dylag, Jeannie Haak, Alessia Angelin, Paolo Bonaldo and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. The transcriptional landscape of developing human trisomy 21 lungs.American journal of respiratory cell and molecular biology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Lung disease manifestations in Down syndrome.American journal of physiology. Lung cellular and molecular physiology · 2021
    Review
  12. Article
  13. Review
  14. Article
  15. Original Article: Clinical Research.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Jared A MerenessDivision of Neonatology and Pediatric Molecular and Personalized Medicine Program, Department of Pediatrics, University of Rochester, Rochester, New York; Department of Biomedical Genetics, University of Rochester, Rochester, New York.
Soumyaroop BhattacharyaDivision of Neonatology and Pediatric Molecular and Personalized Medicine Program, Department of Pediatrics, University of Rochester, Rochester, New York.
Yue RenDivision of Neonatology and Pediatric Molecular and Personalized Medicine Program, Department of Pediatrics, University of Rochester, Rochester, New York.
Qian WangDivision of Neonatology and Pediatric Molecular and Personalized Medicine Program, Department of Pediatrics, University of Rochester, Rochester, New York.
Christopher S AndersonDivision of Neonatology and Pediatric Molecular and Personalized Medicine Program, Department of Pediatrics, University of Rochester, Rochester, New York.
Kathy DonlonDivision of Neonatology and Pediatric Molecular and Personalized Medicine Program, Department of Pediatrics, University of Rochester, Rochester, New York.
Andrew M DylagDivision of Neonatology and Pediatric Molecular and Personalized Medicine Program, Department of Pediatrics, University of Rochester, Rochester, New York.
Jeannie HaakDivision of Neonatology and Pediatric Molecular and Personalized Medicine Program, Department of Pediatrics, University of Rochester, Rochester, New York.
Alessia AngelinCenter for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia Research Institute, Philadelphia, Pennsylvania.
Paolo BonaldoDepartment of Molecular Medicine, University of Padova, Padova, Italy.
Thomas J MarianiDivision of Neonatology and Pediatric Molecular and Personalized Medicine Program, Department of Pediatrics, University of Rochester, Rochester, New York; Department of Biomedical Genetics, University of Rochester, Rochester, New York. Electronic address: tom_mariani@urmc.rochester.edu.
University of Rochester · USChildren's Hospital of Philadelphia · USUniversity of Padua · ITUniversity of Rochester Medical Center · US

Funding

VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI Martha Susiarjo · 1985 to 2026
$42.8M
Training in Environment ToxicologyT32ES007026 · NIEHS · UNIVERSITY OF ROCHESTER · PI Alison Elder, Marissa Sobolewski Terry · 1985 to 2026
$20.2M
MULTIDISCIPLINARY TRAINING IN PULMONARY RESEARCHT32HL066988 · NHLBI · UNIVERSITY OF ROCHESTER · PI GEORAS, STEVE N, O'REILLY, MICHAEL A · 2001 to 2021
$8.1M
Biorepository for Investigation of Neonatal Diseases of Lung-Normal (BRINDL-NL)U01HL122700 · NHLBI · UNIVERSITY OF ROCHESTER · PI PRYHUBER, GLORIA S · 2014 to 2018
$6.1M
Howard Hughes Medical InstituteNHLBI NIH HHS T32 HL066988NHLBI NIH HHS U01 HL122700NIEHS NIH HHS P30 ES001247NIEHS NIH HHS T32 ES007026
6 · The paper itself

Abstract

Collagen VI (COL6) is known for its role in a spectrum of congenital muscular dystrophies, which are often accompanied by respiratory dysfunction. However, little is known regarding the function of COL6 in the lung. We confirmed the presence of COL6 throughout the basement membrane region of mouse lung tissue. Lung structure and organization were studied in a previously described Col6a1

Indexed as

AnimalsBasement MembraneCell SizeCollagen Type VIEpithelial CellsFemaleLungMaleMiceMice, Inbred C57BLMice, KnockoutPulmonary AlveoliSignal TransductionCol6a1 protein, mouseCollagen Type VI

Identifiers

PMID31837950
PMCPMC7013274
OpenAlexW2997218321

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.