Evidence map›Paper›PMID 31837826›Full record

ReviewTrends in genetics : TIG2020

New Roles for Canonical Transcription Factors in Repeat Expansion Diseases.

Lindsey D Goodman, Nancy M Bonini

Open access · greenAbstract readReview
In one paragraph

Review in Trends in genetics : TIG, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Repeat expansions inbioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Review
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  7. Review
  8. The international exchange of Drosophila melanogaster strains.Revue scientifique et technique (International Office of Epizootics) · 2022
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Where and Why Modeling Amyotrophic Lateral Sclerosis.International journal of molecular sciences · 2021
    Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Lindsey D GoodmanDepartment of Molecular and Human Genetics, Neurological Research Institute, Baylor College of Medicine, Houston, TX 77030, USA.
Nancy M BoniniDepartment of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: nbonini@sas.upenn.edu.
Baylor College of Medicine · USUniversity of Pennsylvania · US

Funding

SYSTEMS AND INTEGRATIVE BIOLOGYT32GM007517 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI GOLD, JOSHUA I · 1985 to 2017
$8.0M
Molecular Genetic Insight into Neurodegenerative Disease from DrosophilaR35NS097275 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI BONINI, NANCY M · 2017 to 2024
$6.0M
Epigenetic Changes associated with Neurodegenerative DiseasesR01NS078283 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI BERGER, SHELLEY L, BONINI, NANCY M · 2012 to 2016
$3.3M
SYNAPTOBREVIN AND NEUROTRANSMITTER RELEASEF32NS009727 · NINDS · STANFORD UNIVERSITY · PI DEITCHER, DAVID L · 1994 to 1996
–
NIGMS NIH HHS T32 GM007517NINDS NIH HHS F32 NS009727NINDS NIH HHS R01 NS078283NINDS NIH HHS R35 NS097275
6 · The paper itself

Abstract

The presence of microsatellite repeat expansions within genes is associated with >30 neurological diseases. Of interest, (GGGGCC)

Indexed as

Transcription, GeneticAmyotrophic Lateral SclerosisC9orf72 ProteinDNA Repeat ExpansionFrontotemporal DementiaGC Rich SequenceHumansMicrosatellite RepeatsNeuronsPeptidesRNARNA Polymerase IITranscription FactorsC9orf72 ProteinC9orf72 protein, humanPeptidesRNARNA Polymerase IITranscription FactorsALS/FTDC9orf72DrosophilaDSIF complexPAF1Ctranscription

Identifiers

PMID31837826
PMCPMC6980727
OpenAlexW2995287585

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.