Evidence map›Paper›PMID 31837520›Full record

ReviewiScience2019

Endogenous Bioelectrics in Development, Cancer, and Regeneration: Drugs and Bioelectronic Devices as Electroceuticals for Regenerative Medicine.

Michael Levin, John Selberg, Marco Rolandi

Abstract readReview
In one paragraph

Review in iScience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Bioelectronics forNanotheranostics · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Bioelectricity in dental medicine: a narrative review.Biomedical engineering online · 2024
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Analysis of Electric Field Stimulation in Blue Light Stressed 661W Cells.International journal of molecular sciences · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael LevinAllen Discovery Center at Tufts University, Medford, MA 02155, USA. Electronic address: michael.levin@tufts.edu.
John SelbergElectrical and Computer Engineering Department, University of California, Santa Cruz, CA 95064, USA.
Marco RolandiElectrical and Computer Engineering Department, University of California, Santa Cruz, CA 95064, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A major frontier in the post-genomic era is the investigation of the control of coordinated growth and three-dimensional form. Dynamic remodeling of complex organs in regulative embryogenesis, regeneration, and cancer reveals that cells and tissues make decisions that implement complex anatomical outcomes. It is now essential to understand not only the genetics that specifies cellular hardware but also the physiological software that implements tissue-level plasticity and robust morphogenesis. Here, we review recent discoveries about the endogenous mechanisms of bioelectrical communication among non-neural cells that enables them to cooperate in vivo. We discuss important advances in bioelectronics, as well as computational and pharmacological tools that are enabling the taming of biophysical controls toward applications in regenerative medicine and synthetic bioengineering.

Indexed as

Bioelectrical EngineeringBioelectronicsBiomedical MaterialsBiotechnologyDevelopmental BiologyElectronic Materials

Identifiers

PMID31837520
PMCPMC6920204

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.