Evidence map›Paper›PMID 31837320›Full record

ReviewExperimental neurology2020

NAD

Nina Klimova, Adam Fearnow, Aaron Long, Tibor Kristian

Open access · greenAbstract readReview
In one paragraph

Review in Experimental neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 1 synthesis or guideline pooled it, 105 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Exercise benefits in metabolism on cardiovascular disease.Frontiers in cardiovascular medicine · 2026
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. β-Nicotinamide mononucleotide blocks UVB-induced collagen reduction via regulation of ROS/MAPK/AP-1 and stimulation of mitochondrial proline biosynthesis.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  17. Decrease of NADJournal of inflammation research · 2025
    Article
  18. Article
  19. Nicotinamide Mononucleotide Restores NADAntioxidants (Basel, Switzerland) · 2024
    Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nina KlimovaDepartment of Anesthesiology and the Center for Shock, Trauma, and Anesthesiology Research (S.T.A.R.), University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Adam FearnowVeterans Affairs Maryland Health Center System, 10 North Greene Street, Baltimore, MD 21201, USA.
Aaron LongVeterans Affairs Maryland Health Center System, 10 North Greene Street, Baltimore, MD 21201, USA.
Tibor KristianVeterans Affairs Maryland Health Center System, 10 North Greene Street, Baltimore, MD 21201, USA; Department of Anesthesiology and the Center for Shock, Trauma, and Anesthesiology Research (S.T.A.R.), University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address: tkristian@som.umaryland.edu.
University of Maryland, Baltimore · USVA Maryland Health Care System · US

Funding

The role of nicotinamide mononucleotide dependent mitochondrial reactive oxygen species generation in acute brain injuryI01BX004895 · VA · BALTIMORE VA MEDICAL CENTER · PI KRISTIAN, TIBOR · 2020 to 2024
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BLRD VA I01 BX004895
6 · The paper itself

Abstract

Global cerebral ischemia depletes brain tissue NAD

Indexed as

AnimalsBrain IschemiaHippocampusMaleMiceMice, Inbred C57BLMice, TransgenicMitochondriaNADNeuronsNicotinamide MononucleotideReactive Oxygen SpeciesSirtuin 3NADNicotinamide MononucleotideReactive Oxygen SpeciesSirt3 protein, mouseSirtuin 3AcetylationFree radicalsGlobal cerebral ischemiaMitochondriaMitochondrial dynamicsNAD(+)

Identifiers

PMID31837320
PMCPMC8328278
OpenAlexW2996682146

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.