Evidence map›Paper›PMID 31837182›Full record

ArticleJournal of veterinary internal medicine2020

Cardiac cachexia in cats with congestive heart failure: Prevalence and clinical, laboratory, and survival findings.

Sasha L Santiago, Lisa M Freeman, John E Rush

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Feline comorbidities: cardiovascular and kidney diseases.Journal of feline medicine and surgery · 2026
    Review
  2. Article
  3. Article
  4. Falciform fat:femur length ratio provides a novel method for objective postmortem estimation of total body fat in overweight and obese cats.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sasha L SantiagoDepartment of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts.
Lisa M FreemanDepartment of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts.ORCID https://orcid.org/0000-0002-0569-9557
John E RushDepartment of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts.ORCID https://orcid.org/0000-0002-8277-8996
Tufts University · US

Funding

Barkley Fund
6 · The paper itself

Abstract

backgroundCardiac cachexia is common in people and dogs with congestive heart failure (CHF). However, the prevalence and effects of cardiac cachexia in cats are unknown.

objectivesTo determine the prevalence of cachexia and its associations with clinical laboratory and survival data in cats with CHF. ANIMALS: One hundred twenty-five cats with CHF.

methodsMedical records of cats evaluated during a 40-month period were retrospectively reviewed to identify cats with cardiac cachexia using 7 different definitions. Clinical, laboratory, and survival data were compared between cats with and without cachexia.

resultsPrevalence of cachexia ranged from 0 to 66.7% for the 7 definitions, with a prevalence of 41.6% using muscle condition score (MCS). Cats with cachexia (determined by MCS) were older (P < .001), more likely to have pleural effusion (P = .003), had significantly higher blood urea nitrogen (P < .001) and neutrophil concentrations (P = .01), and significantly lower body condition score (P < .001), body weights (P < .001), hematocrit (P = .007), and hemoglobin concentrations (P = .009). Survival time for cats with cachexia (determined by MCS) was significantly shorter than for cats without cachexia (P = .03). Cats that were underweight (P = .002) and cats with dilated cardiomyopathy (DCM) also had shorter survival times (P = .04). CONCLUSIONS AND CLINICAL IMPORTANCE: The association between cachexia and reduced survival time emphasizes the importance of identifying and addressing this common problem in cats with CHF.

Indexed as

AnimalsCachexiaCat DiseasesCatsFemaleHeart FailureLongevityMalecardiologycardiomyopathycongestive heart failuremusclenutrition

Identifiers

PMID31837182
PMCPMC6979101
OpenAlexW2994386458

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.