ArticleEuropean journal of nuclear medicine and molecular imaging2020
Combined evaluation of regional coronary artery calcium and myocardial perfusion by
Article in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 40 citations in OpenAlex.
- Long term prognostic value of coronary atherosclerotic burden, myocardial perfusion and coronary flow capacity byEuropean journal of nuclear medicine and molecular imaging · 2026Article
- Multicenter evaluation of interpretable AI for coronary artery disease diagnosis from PET biomarkers.NPJ digital medicine · 2026Article
- Deep learning-quantified body composition from positron emission tomography/computed tomography and cardiovascular outcomes: a multicentre study.European heart journal · 2025Article
- Emerging Applications of Positron Emission Tomography in Coronary Artery Disease.Journal of personalized medicine · 2025Review
- Prognostic Value of Coronary Flow Capacity byCirculation. Cardiovascular imaging · 2024Article
- The prognostic value of visual and automatic coronary calcium scoring from low-dose computed tomography-[15O]-water positron emission tomography.European heart journal. Cardiovascular Imaging · 2024Article
- Impact on cardiovascular outcome of coronary revascularization-induced changes in ischemic perfusion defect and myocardial flow reserve.European journal of nuclear medicine and molecular imaging · 2024Article
- Comparing various AI approaches to traditional quantitative assessment of the myocardial perfusion in [Scientific reports · 2024Article
- Combined evaluation of CAC score and myocardial perfusion imaging in patients at risk of cardiovascular disease: where are we and what do the data say.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Review
- Including myocardial flow reserve by PET in prediction models: Ready to fly?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Comparison of the prognostic value of impaired stress myocardial blood flow, myocardial flow reserve, and myocardial flow capacity on low-dose Rubidium-82 SiPM PET/CT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Prediction of outcome byJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Low-dose coronary calcium scoring tarnishes power of zero.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- The addition of coronary artery calcium to myocardial perfusion: Double or nothing?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Regional myocardial perfusion imaging in predicting vessel-related outcome: interplay between the perfusion results and angiographic findings.European journal of nuclear medicine and molecular imaging · 2022Article
- Cardiac imaging for the assessment of patients being evaluated for liver transplantation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Review
- Diagnostic value of clinical risk scores for predicting normal stress myocardial perfusion imaging in subjects without coronary artery calcium.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Vasodilators and myocardial blood flow by CZT cameras: Make us see further.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Prognostic values of coronary artery calcium score andThe international journal of cardiovascular imaging · 2021Article
- Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCardiac imaging with positron emission tomography/computed tomography (PET/CT) allows measurement of coronary artery calcium (CAC), stress-induced myocardial ischemia and myocardial perfusion reserve (MPR). We evaluated the prognostic role of the combined assessment of regional CAC score, ischemic total perfusion defect (ITPD) and MPR in predicting lesion-related outcome in patients with suspected coronary artery disease (CAD).
methodsWe studied 206 patients with suspected CAD referred to
resultsCompared to vessels without event, those with event showed higher CAC score and ITPD, and lower hyperemic myocardial blood flow and MPR (all p < 0.001). At Cox regression multivariable analysis, significant CAD (≥50% stenosis) (p < 0.001), CAC score ≥ 300 (p < 0.01) and MPR <2 (p < 0.01) were independent predictors of events. The decision trees analysis for the identification of events produced five terminal nodes. The initial split was on CAC score values. For vessels with CAC <300 and MPR ≥2, no further split was performed, while vessels with CAC <300 and MPR <2 were further stratified by ITPD. For vessels with CAC ≥300 a further stratification was performed only by MPR. The worst prognosis was observed in vessels with CAC ≥300 and MPR <2 and in vessels with CAC <300, MPR <2 and ITPD ≥5%.
conclusionThe combination of CAC score and MPR is useful to predict the lesion-related outcome in the presence of significant CAD.
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