Evidence map›Paper›PMID 31836751›Full record

Observational studyScientific reports2019

Frailty is Associated with an Increased Risk of Major Adverse Outcomes in Elderly Patients Following Surgical Treatment of Hip Fracture.

Chiu-Liang Chen, Chun-Min Chen, Chun-Yi Wang, Po-Wei Ko, Chung-Hwan Chen, Chen-Pu Hsieh, Herng-Chia Chiu

Abstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Article
  8. Review
  9. Observational
  10. Review
  11. Article
  12. Article
  13. Article
  14. External validation of an AI-based preoperative frailty index using real-world data.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  15. Factors associated with frailty and the effect of frailty on postoperative outcomes in older adults with hip fracture.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chiu-Liang ChenDepartment of Orthopedic Surgery, Changhua Christian Hospital, Changhua, Taiwan.
Chun-Min ChenResearch Education and Epidemiology Center, Changhua Christian Hospital, Changhua, Taiwan.
Chun-Yi WangDepartment of Orthopedic Surgery, Yuanlin Christian Hospital, Changhua, Taiwan.
Po-Wei KoDepartment of Orthopedic Surgery, Yuanlin Christian Hospital, Changhua, Taiwan.
Chung-Hwan ChenOrthopedic Research Centre, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chen-Pu HsiehDepartment of Orthopedic Surgery, Changhua Christian Hospital, Changhua, Taiwan.
Herng-Chia ChiuInstitute of Hospital Management, Tsinghua University, Beijing, China. chiuhc@sz.tsinghua.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We intended to explore the effect of level of frailty on, and relationship with, 1-, 3-, and 6-month postoperative emergency department visits, readmissions, and mortality. This is a prospective multicenter observational cohort study design. Patients aged 50 years or older treated for hip fracture (n = 245) were taken from Orthopedic wards in one medical center (n = 131) and one district hospital (n = 114) in Changhua County, Taiwan. Frailty was defined as measured by the validated Clinical Frailty Scale and categorized as robust, pre-frail, and frail. We used Kaplan-Meier analysis to estimate survival rates and Cox regression to estimate the risk of frailty associated with adverse outcomes. To examine the longitudinal associations between frailty and adverse outcome, the cross-lagged models were explored. Of the 245 patients, 55 (22.4%) were classified as frail, 113 (46.1%) as pre-frail, and 77 (31.4%) as robust. More cumulative events occurred for frail than for robust patients for each adverse outcome. Frailty has long-term effect on each adverse outcome after discharge, rather than the effect simultaneously. Targeting pre-frailty and frailty is essential for prevent adverse outcomes and improving the overall health of older adults after discharge for hip fracture.

Indexed as

FrailtyAgedAged, 80 and overFemaleFrail ElderlyGeriatric AssessmentHip FracturesHospitalsHumansKaplan-Meier EstimateLongitudinal StudiesMaleMiddle AgedOrthopedicsPostoperative ComplicationsProportional Hazards Models

Identifiers

PMID31836751
PMCPMC6910954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.