Evidence map›Paper›PMID 31836744›Full record

ArticleScientific reports2019

Phonetic relevance and phonemic grouping of speech in the automatic detection of Parkinson's Disease.

Laureano Moro-Velazquez, Jorge A Gomez-Garcia, Juan I Godino-Llorente, Francisco Grandas-Perez, Stefanie Shattuck-Hufnagel, Virginia Yagüe-Jimenez, Najim Dehak

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 59 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Laureano Moro-VelazquezJohns Hopkins University, Department of Electrical and Computer Engineering, Baltimore, 21218, USA. laureano@jhu.edu.ORCID http://orcid.org/0000-0002-3033-7005
Jorge A Gomez-GarciaUniversidad Politécnica de Madrid, Escuela Técnica Superior de Ingeniería y Sistemas de Telecomunicación, Madrid, 28031, Spain.
Juan I Godino-LlorenteUniversidad Politécnica de Madrid, Escuela Técnica Superior de Ingeniería y Sistemas de Telecomunicación, Madrid, 28031, Spain.
Francisco Grandas-PerezHospital General Universitario Gregorio Marãnón, Madrid, 28007, Spain.
Stefanie Shattuck-HufnagelMassachusetts Institute of Technology, Speech Communication Group, Cambridge, 02139, USA.
Virginia Yagüe-JimenezConsejo Superior de Investigaciones Científicas, Centro de Tecnologías Físicas Leonardo Torres Quevedo, Madrid, 28006, Spain.
Najim DehakJohns Hopkins University, Department of Electrical and Computer Engineering, Baltimore, 21218, USA.
Johns Hopkins University · USUniversidad Politécnica de Madrid · ESConsejo Superior de Investigaciones Científicas · ESHospital General Universitario Gregorio Marañón · ESMassachusetts Institute of Technology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Literature documents the impact of Parkinson's Disease (PD) on speech but no study has analyzed in detail the importance of the distinct phonemic groups for the automatic identification of the disease. This study presents new approaches that are evaluated in three different corpora containing speakers suffering from PD with two main objectives: to investigate the influence of the different phonemic groups in the detection of PD and to propose more accurate detection schemes employing speech. The proposed methodology uses GMM-UBM classifiers combined with a technique introduced in this paper called phonemic grouping, that permits observation of the differences in accuracy depending on the manner of articulation. Cross-validation results reach accuracies between 85% and 94% with AUC ranging from 0.91 to 0.98, while cross-corpora trials yield accuracies between 75% and 82% with AUC between 0.84 and 0.95, depending on the corpus. This is the first work analyzing the generalization properties of the proposed approaches employing cross-corpora trials and reaching high accuracies. Among the different phonemic groups, results suggest that plosives, vowels and fricatives are the most relevant acoustic segments for the detection of PD with the proposed schemes. In addition, the use of text-dependent utterances leads to more consistent and accurate models.

Indexed as

PhoneticsAdultAgedAged, 80 and overArea Under CurveFemaleHumansMaleMiddle AgedParkinson DiseaseSound SpectrographySpeech

Identifiers

PMID31836744
PMCPMC6910953
OpenAlexW2995382111

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.