Evidence map›Paper›PMID 31836580›Full record

ArticleApplied and environmental microbiology2020

Melanin Produced by the Fast-Growing Marine Bacterium Vibrio natriegens through Heterologous Biosynthesis: Characterization and Application.

Zheng Wang, Tanya Tschirhart, Zachary Schultzhaus, Erin E Kelly, Amy Chen, Eunkeu Oh, Okhil Nag, Evan R Glaser, Eunkyoung Kim, Pamela F Lloyd and 8 more

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 96 citations in OpenAlex.

  1. Metabolic engineering ofSynthetic and systems biotechnology · 2026
    Article
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  11. Vibrio natriegens: Application of a Fast-Growing Halophilic Bacterium.Advances in biochemical engineering/biotechnology · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Ploidy inGenes · 2023
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

Zheng WangCenter for Biomolecular Science and Engineering, Naval Research Laboratory, Washington, DC, USA zheng.wang@nrl.navy.mil gary.vora@nrl.navy.mil.ORCID 0000-0001-6504-888X
Tanya TschirhartCenter for Biomolecular Science and Engineering, Naval Research Laboratory, Washington, DC, USA.
Zachary SchultzhausNational Research Council Postdoctoral Research Associate, Naval Research Laboratory, Washington, DC, USA.
Erin E KellyNational Research Council Postdoctoral Research Associate, Naval Research Laboratory, Washington, DC, USA.
Amy ChenCenter for Biomolecular Science and Engineering, Naval Research Laboratory, Washington, DC, USA.
Eunkeu OhOptical Sciences Division, Naval Research Laboratory, Washington, DC, USA.
Okhil NagCenter for Biomolecular Science and Engineering, Naval Research Laboratory, Washington, DC, USA.
Evan R GlaserDivision of Electronics Science and Technology, Naval Research Laboratory, Washington, DC, USA.
Eunkyoung KimInstitute for Bioscience and Biotechnology Research, University of Maryland, College Park, Maryland, USA.
Pamela F LloydUES, Inc., Wright-Patterson Air Force Base, Ohio, USA.
Paul T CharlesCenter for Biomolecular Science and Engineering, Naval Research Laboratory, Washington, DC, USA.
Weiyao LiDepartment of Polymer Science, The University of Akron, Akron, Ohio, USA.
Dagmar LearyCenter for Biomolecular Science and Engineering, Naval Research Laboratory, Washington, DC, USA.
Jaimee ComptonCenter for Biomolecular Science and Engineering, Naval Research Laboratory, Washington, DC, USA.
Daniel A PhillipsNational Research Council Postdoctoral Research Associate, Naval Research Laboratory, Washington, DC, USA.
Ali DhinojwalaDepartment of Polymer Science, The University of Akron, Akron, Ohio, USA.
Gregory F PayneInstitute for Bioscience and Biotechnology Research, University of Maryland, College Park, Maryland, USA.
Gary J VoraCenter for Biomolecular Science and Engineering, Naval Research Laboratory, Washington, DC, USA zheng.wang@nrl.navy.mil gary.vora@nrl.navy.mil.ORCID 0000-0002-0657-8597
United States Naval Research Laboratory · USNational Academies of Sciences, Engineering, and Medicine · USUniversity of Akron · USUniversity of Maryland, College Park · USWright-Patterson Air Force Base · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanin is a pigment produced by organisms throughout all domains of life. Due to its unique physicochemical properties, biocompatibility, and biostability, there has been an increasing interest in the use of melanin for broad applications. In the vast majority of studies, melanin has been either chemically synthesized or isolated from animals, which has restricted its use to small-scale applications. Using bacteria as biocatalysts is a promising and economical alternative for the large-scale production of biomaterials. In this study, we engineered the marine bacterium

Indexed as

Bacillus megateriumBiopolymersMelaninsMicroorganisms, Genetically-ModifiedMonophenol MonooxygenaseVibrioBiopolymersMelaninsMonophenol Monooxygenasebiomanufacturingfast growingmelaninmelanin biosynthesisnanoparticlesynthetic biologyVibrio natriegens

Identifiers

PMID31836580
PMCPMC7028964
OpenAlexW2994866620

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.