Evidence map›Paper›PMID 31836447›Full record

ArticleBioorganic & medicinal chemistry letters2020

Enhancing the incorporation of lysine derivatives into proteins with methylester forms of unnatural amino acids.

Han Zhou, Jenny W Cheung, Tomaya Carpenter, Stacey K Jones, Nhu H Luong, Nhi C Tran, Savannah E Jacobs, Sahan A Galbada Liyanage, T Ashton Cropp, Jun Yin

Abstract read
In one paragraph

Article in Bioorganic & medicinal chemistry letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Genetic Encoding of a Photocaged Histidine for Light-Control of Protein Activity.Chembiochem : a European journal of chemical biology · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Efficient Amber SuppressionACS synthetic biology · 2022
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Han ZhouDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30302, United States.
Jenny W CheungDepartment of Chemistry, Virginia Commonwealth University, Richmond, VA 23284, United States.
Tomaya CarpenterDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30302, United States.
Stacey K JonesDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30302, United States.
Nhu H LuongDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30302, United States.
Nhi C TranDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30302, United States.
Savannah E JacobsDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30302, United States.
Sahan A Galbada LiyanageDepartment of Chemistry, Virginia Commonwealth University, Richmond, VA 23284, United States.
T Ashton CroppDepartment of Chemistry, Virginia Commonwealth University, Richmond, VA 23284, United States; Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA 23219, United States. Electronic address: tacropp@vcu.edu.
Jun YinDepartment of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30302, United States. Electronic address: junyin@gsu.edu.

Funding

Orthogonal Ubiquitin Transfer to Profile E3 Substrate Specificity.R01GM104498 · NIGMS · UNIVERSITY OF CHICAGO · PI KIYOKAWA, HIROAKI, YIN, JUN · 2013 to 2021
$3.2M
Insights into Gordon Holmes syndrome by substrate profiling of Triad3A and Chip using Orthogonal Ubiquitin TransferR21NS116760 · NINDS · GEORGIA STATE UNIVERSITY · PI MABB, ANGELA M, YIN, JUN · 2021 to 2021
$429k
NIGMS NIH HHS R01 GM104498NINDS NIH HHS R21 NS116760
6 · The paper itself

Abstract

We have improved the incorporation of l- and d-forms of unnatural amino acid (UAA) N

Indexed as

Amino AcidsLysineMolecular StructureStructure-Activity RelationshipAmino AcidsLysineAminoacyl-tRNA synthetaseMethyl esterProtein expressionUbiquitinUnnatural amino acid

Identifiers

PMID31836447
PMCPMC7644286

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.