Evidence map›Paper›PMID 31836342›Full record

ArticleThe American journal of emergency medicine2020

Predictors of linkage to care for a nontargeted emergency department hepatitis C screening program.

Joshua A Blackwell, Joel B Rodgers, Ricardo A Franco, Stacey S Cofield, Lauren A Walter, James W Galbraith, Erik P Hess

Abstract read
In one paragraph

Article in The American journal of emergency medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Hepatitis C Virus Reflex Testing Protocol in an Emergency Department.The western journal of emergency medicine · 2022
    Article
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  19. Article
  20. Linkage to specialty care in the hepatitis C care cascade.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joshua A BlackwellUniversity of Alabama School of Medicine, 1670 University Blvd, Birmingham, AL 35233, USA; UAB School of Public Health, 1665 University Blvd, Birmingham, AL 35233, USA. Electronic address: jablackw@uab.edu.
Joel B RodgersDepartment of Emergency Medicine, UAB School of Medicine, Old Hillman Building #251, 619 South 19th Street, Birmingham, AL 35249, USA.
Ricardo A FrancoDivision of Infectious Diseases, Department of Medicine, UAB School of Medicine, 1900 University Boulevard, THT 229, Birmingham, AL 35294, USA.
Stacey S CofieldDepartment of Biostatistics, University of Alabama at Birmingham, 1665 University Blvd #327, Birmingham, AL 35294, USA.
Lauren A WalterUniversity of Alabama School of Medicine, 1670 University Blvd, Birmingham, AL 35233, USA; Department of Emergency Medicine, UAB School of Medicine, Old Hillman Building #251, 619 South 19th Street, Birmingham, AL 35249, USA.
James W GalbraithDepartment of Emergency Medicine, University of Mississippi Medical Center, 2500 N. State Street, Jackson, MS 39216, USA.
Erik P HessUniversity of Alabama School of Medicine, 1670 University Blvd, Birmingham, AL 35233, USA; Department of Emergency Medicine, UAB School of Medicine, Old Hillman Building #251, 619 South 19th Street, Birmingham, AL 35249, USA.

Funding

UAB Center for Clinical and Translational Sciences (CCTS)TL1TR001418 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SAAG, KENNETH G · 2015 to 2018
$2.1M
NCATS NIH HHS TL1 TR001418
6 · The paper itself

Abstract

objectiveWe implemented a nontargeted, opt-out HCV testing and linkage to care (LTC) program in an academic tertiary care emergency department (ED). Despite research showing the critical role of ED-based HCV testing programs, predictors of LTC have not been defined for patients identified through the nontargeted ED testing strategy. In order to optimize health outcomes for patients with HCV, we sought to identify predictors of LTC failure.

methodsThis was a retrospective cohort study of adult patients who were tested for HCV in the ED between August 2015 and September 2018 and were confirmed to have chronic HCV infection through RNA testing. We used logistic regression to assess the relationship between candidate predictors and the primary outcome, LTC failure, which was defined as a patient not being seen by an HCV treating provider after discharge from the ED.

resultsOf 53,297 patients tested, 1,674 (3.1%) had HCV on confirmatory testing, and 355 (21%) linked to care. Predictors of LTC failure included younger age (OR 0.96, 95% CI 0.95-0.97), white race (OR 1.65, 95% CI 1.23-2.22), homelessness (OR 1.91, 95% CI 1.19-3.08), substance use (OR 1.77, 95% CI 1.34-2.34), and comorbid psychiatric illness (OR 2.16, 95% CI 1.59-2.94). Patients with significant medical comorbidities (OR 0.57, 95% CI 0.41-0.78) or HIV co-infection (OR 0.11, 95% CI 0.03-0.46) were less likely to experience LTC failure.

conclusionsOne in five HCV-infected patients identified by ED-based nontargeted testing successfully linked to an HCV treating provider. Predictors of LTC failure may guide the development of targeted interventions to improve LTC success.

Indexed as

AdultAge FactorsAlabamaCohort StudiesComorbidityContinuity of Patient CareEmergency Service, HospitalEthnicityFemaleHepatitis C AntibodiesHepatitis C, ChronicHIV InfectionsHumansIll-Housed PersonsLogistic ModelsMaleHepatitis C AntibodiesRNA, ViralHCVHepatitis CLinkage to careNontargeted screeningOpt-out screeningTargeted screening

Identifiers

PMID31836342
PMCPMC7255936

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.