ArticleNeuron2020
The Transition from Evaluation to Selection Involves Neural Subspace Reorganization in Core Reward Regions.
Article in Neuron, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Article
- Role of the primate ventral striatum as a neural hub bridging option valuation and action selection.Nature communications · 2026Article
- Neural geometry in the human hippocampus enables generalization across spatial position and gaze.ArXiv · 2026Article
- Rethinking the centrality of brain areas in understanding functional organization.Nature neuroscience · 2026Review
- Humans and neural networks show similar patterns of transfer and interference during continual learning.Nature human behaviour · 2026Article
- The Primate Hippocampus Constructs a Temporal Scaffold Anchored to Behavioral Events.bioRxiv : the preprint server for biology · 2025Article
- A posture subspace in the primary motor cortex.Neuron · 2025Article
- Robustness of Working Memory to Prefrontal Cortex Microstimulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- A transformation from vision to imagery in the human brain.bioRxiv : the preprint server for biology · 2025Article
- A neural manifold view of the brain.Nature neuroscience · 2025Review
- Novel Verbal Instructions Recruit Abstract Neural Patterns of Time-Variable Information Dimensionality.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Robustness of working memory to prefrontal cortex microstimulation.bioRxiv : the preprint server for biology · 2025Article
- Coordinated representations for naturalistic memory encoding and retrieval in hippocampal neural subspaces.Nature communications · 2025Article
- Semi-orthogonal subspaces for value mediate a binding and generalization trade-off.Nature neuroscience · 2024Article
- Rational inattention in neural coding for economic choice.bioRxiv : the preprint server for biology · 2024Article
- A computational mechanism of cue-stimulus integration for pain in the brain.Science advances · 2024Article
- Gaze-centered gating, reactivation, and reevaluation of economic value in orbitofrontal cortex.Nature communications · 2024Article
- Review
- Insula uses overlapping codes for emotion in self and others.bioRxiv : the preprint server for biology · 2024Article
- Cognition is an emergent property.Current opinion in behavioral sciences · 2024Article
Corrections and comments
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2 authors.
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Abstract
Economic choice proceeds from evaluation, in which we contemplate options, to selection, in which we weigh options and choose one. These stages must be differentiated so that decision makers do not proceed to selection before evaluation is complete. We examined responses of neurons in two core reward regions, orbitofrontal (OFC) and ventromedial prefrontal cortex (vmPFC), during two-option choice with asynchronous offer presentation. Our data suggest that neurons selective during the first (presumed evaluation) and second (presumed comparison and selection) offer epochs come from a single pool. Stage transition is accompanied by a shift toward orthogonality in the low-dimensional population response manifold. Nonetheless, the relative position of each option in driving responses in the population subspace is preserved. The orthogonalization we observe supports the hypothesis that the transition from evaluation to selection leads to reorganization of response subspace and suggests a mechanism by which value-related signals are prevented from prematurely driving choice.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.