Evidence map›Paper›PMID 31835854›Full record

ArticleCells2019

18F-FDG PET-Based Imaging of Myocardial Inflammation Predicts a Functional Outcome Following Transplantation of mESC-Derived Cardiac Induced Cells in a Mouse Model of Myocardial Infarction.

Praveen Vasudevan, Ralf Gaebel, Piet Doering, Paula Mueller, Heiko Lemcke, Jan Stenzel, Tobias Lindner, Jens Kurth, Gustav Steinhoff, Brigitte Vollmar and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  4. New Approaches in Heart Research: Prevention Instead of Cardiomyoplasty?International journal of molecular sciences · 2023
    Review
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  10. Article
  11. HyperpolarizedNMR in biomedicine · 2021
    Review
  12. Review
  13. Article
  14. [Cells · 2020
    Article
  15. International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Praveen VasudevanDepartment of Cardiac Surgery, Rostock University Medical Center, 18057 Rostock, Germany.
Ralf GaebelDepartment of Cardiac Surgery, Rostock University Medical Center, 18057 Rostock, Germany.
Piet DoeringDepartment of Nuclear Medicine, Rostock University Medical Center, 18057 Rostock, Germany.
Paula MuellerDepartment of Cardiac Surgery, Rostock University Medical Center, 18057 Rostock, Germany.
Heiko LemckeDepartment of Cardiac Surgery, Rostock University Medical Center, 18057 Rostock, Germany.
Jan StenzelCore Facility Multimodal Small Animal Imaging, Rostock University Medical Center, 18057 Rostock, Germany.
Tobias LindnerCore Facility Multimodal Small Animal Imaging, Rostock University Medical Center, 18057 Rostock, Germany.
Jens KurthDepartment of Nuclear Medicine, Rostock University Medical Center, 18057 Rostock, Germany.
Gustav SteinhoffDepartment of Cardiac Surgery, Rostock University Medical Center, 18057 Rostock, Germany.
Brigitte VollmarCore Facility Multimodal Small Animal Imaging, Rostock University Medical Center, 18057 Rostock, Germany.
Bernd Joachim KrauseDepartment of Nuclear Medicine, Rostock University Medical Center, 18057 Rostock, Germany.
Hueseyin InceDepartment of Cardiology, Rostock University Medical Center, 18057 Rostock, Germany.
Robert DavidDepartment of Cardiac Surgery, Rostock University Medical Center, 18057 Rostock, Germany.
Cajetan Immanuel LangDepartment of Cardiology, Rostock University Medical Center, 18057 Rostock, Germany.
University of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellular inflammation following acute myocardial infarction has gained increasing importance as a target mechanism for therapeutic approaches. We sought to investigate the effect of syngeneic cardiac induced cells (CiC) on myocardial inflammation using 18F-FDG PET (Positron emission tomography)-based imaging and the resulting effect on cardiac pump function using cardiac magnetic resonance (CMR) imaging in a mouse model of myocardial infarction. Mice underwent permanent left anterior descending coronary artery (LAD) ligation inducing an acute inflammatory response. The therapy group received an intramyocardial injection of 10

Indexed as

AnimalsCD11 AntigensCells, CulturedDisease Models, AnimalFluorodeoxyglucose F18HeartHumansMagnetic Resonance Imaging, CineMiceMouse Embryonic Stem CellsMyocardial InfarctionPositron-Emission TomographyTreatment OutcomeVentricular Function, LeftCD11 AntigensFluorodeoxyglucose F1818F-FDG PETcardiac functioncardiac induced cellscardiomyocytesinflammationnon-invasive imaging

Identifiers

PMID31835854
PMCPMC6952872
OpenAlexW2995309111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.