Evidence map›Paper›PMID 31835763›Full record

ArticleJournal of clinical medicine2019

One-Stop Management of 230 Consecutive Acute Stroke Patients: Report of Procedural Times and Clinical Outcome.

Marios-Nikos Psychogios, Ilko L Maier, Ioannis Tsogkas, Amélie Carolina Hesse, Alex Brehm, Daniel Behme, Marlena Schnieder, Katharina Schregel, Ismini Papageorgiou, David S Liebeskind and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07052045 (One-Stop manaGemEnT For A Swift Initiation of Endovascular Therapy - An International, Multicenter, Pragmatic Randomized Controlled Trial), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07052045 narecruitingnot on this mapstarted 2025, after this paper: background citation

One-Stop manaGemEnT For A Swift Initiation of Endovascular Therapy - An International, Multicenter, Pragmatic Randomized Controlled Trial (GET-FAST

TypeinterventionalSponsorProf. Dr. Jan LimanRan2025 to 2028Enrolled390ConditionsStroke Acute, Acute Ischemic Stroke AIS, Hemorrhagic Stroke, IntracerebralArmsOne Stop Management, Usual care management
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  7. Direct to hybrid CT-angiosuite (Nexaris) reduces treatment time for stroke thrombectomy (Direct-ST): A prospective simulation study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Marios-Nikos PsychogiosDepartment of Neuroradiology, University Medical Center Goettingen, 37075 Goettingen, Germany.
Ilko L MaierDepartment of Neurology, University Medical Center Goettingen, 37075 Goettingen, Germany.ORCID 0000-0001-6988-8878
Ioannis TsogkasDepartment of Neuroradiology, University Medical Center Goettingen, 37075 Goettingen, Germany.
Amélie Carolina HesseDepartment of Neuroradiology, University Medical Center Goettingen, 37075 Goettingen, Germany.
Alex BrehmDepartment of Neuroradiology, University Medical Center Goettingen, 37075 Goettingen, Germany.ORCID 0000-0002-1630-6210
Daniel BehmeDepartment of Neuroradiology, University Medical Center Goettingen, 37075 Goettingen, Germany.
Marlena SchniederDepartment of Neurology, University Medical Center Goettingen, 37075 Goettingen, Germany.
Katharina SchregelDepartment of Neuroradiology, University Medical Center Goettingen, 37075 Goettingen, Germany.
Ismini PapageorgiouDepartment of Neuroradiology, Südharz Klinikum, 99734 Nordhausen, Germany.ORCID 0000-0001-5810-0483
David S LiebeskindNeurovascular Imaging Research Core and Stroke Center, Department of Neurology, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-5109-8736
Mayank GoyalCalgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, Calgary, AB 2500, Canada.
Mathias BährDepartment of Neurology, University Medical Center Goettingen, 37075 Goettingen, Germany.
Michael KnauthDepartment of Neuroradiology, University Medical Center Goettingen, 37075 Goettingen, Germany.
Jan LimanDepartment of Neurology, University Medical Center Goettingen, 37075 Goettingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeRapid thrombectomy for acute ischemic stroke caused by large vessel occlusion leads to improved outcome. Optimizing intrahospital management might diminish treatment delays. To examine if one-stop management reduces intrahospital treatment delays and improves functional outcome of acute stroke patients with large vessel occlusion.

methodsWe performed a single center, observational study from June 2016 to November 2018. Imaging was acquired with the latest generation angiography suite at a comprehensive stroke center. Two-hundred-thirty consecutive adults with suspected acute stroke presenting within 6 h after symptom onset with a moderate to severe National Institutes of Health Stroke Scale (≥10 in 2016; ≥7 since January 2017) were directly transported to the angiography suite by bypassing multidetector CT. Noncontrast flat-detector CT and biphasic flat-detector CT angiography were acquired with an angiography system. In case of a large vessel occlusion patients remained in the angiography suite, received intravenous rtPA therapy and underwent thrombectomy. As primary endpoints, door-to-reperfusion times and functional outcome at 90 days were recorded and compared in a case-control analysis with matched prior patients receiving standard management.

resultsA total of 230 patients (123 women, median age of 78 years (Interquartile Range (IQR) 69-84)) were included. Median symptom-to-door time was 130 min (IQR 70-195). Large vessel occlusion was diagnosed in 166/230 (72%) patients; 64/230 (28%) had conditions not suitable for thrombectomy. Median door-to-reperfusion time for M1 occlusions was 64 min (IQR 56-87). Compared to 43 case-matched patients triaged with multidetector CT, median door-to-reperfusion time was reduced from 102 (IQR 85-117) to 68 min (IQR 53-89;

conclusionsOne-stop management for stroke triage reduces intrahospital time delays in our specific hospital setting.

Indexed as

cerebral angiographycone-beam computed tomographyhemorrhagestrokethrombectomy

Identifiers

PMID31835763
PMCPMC6947228

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.