Evidence map›Paper›PMID 31835716›Full record

ArticleInternational journal of molecular sciences2019

Novel Drug-Like Somatostatin Receptor 4 Agonists are Potential Analgesics for Neuropathic Pain.

Boglárka Kántás, Rita Börzsei, Éva Szőke, Péter Bánhegyi, Ádám Horváth, Ágnes Hunyady, Éva Borbély, Csaba Hetényi, Erika Pintér, Zsuzsanna Helyes

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Human Somatostatin SSTInternational journal of molecular sciences · 2021
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Frontiers in pharmacology · 2020
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Boglárka KántásDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti str. 12, H-7624 Pécs, Hungary.
Rita BörzseiDepartment of Pharmacology, Faculty of Pharmacy, University of Pécs, Szigeti str. 12, H-7624 Pécs, Hungary.
Éva SzőkeDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti str. 12, H-7624 Pécs, Hungary.
Péter BánhegyiAvicor Ltd., Herman Ottó str. 15, H-1022 Budapest, Hungary.
Ádám HorváthDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti str. 12, H-7624 Pécs, Hungary.
Ágnes HunyadyDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti str. 12, H-7624 Pécs, Hungary.
Éva BorbélyDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti str. 12, H-7624 Pécs, Hungary.
Csaba HetényiDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti str. 12, H-7624 Pécs, Hungary.
Erika PintérDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti str. 12, H-7624 Pécs, Hungary.
Zsuzsanna HelyesDepartment of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti str. 12, H-7624 Pécs, Hungary.
University of Pecs · HU

Funding

Ministry for Innovation and Technology-Hungary ÚNKP-19-4 New National Excellence ProgramNemzeti Kutatási Fejlesztési és Innovációs Hivatal 2017-1.2.1-NKP-2017-00002Nemzeti Kutatási Fejlesztési és Innovációs Hivatal EFOP-3.6.1.-16-2016-0004Nemzeti Kutatási Fejlesztési és Innovációs Hivatal EFOP-3.6.2-16-2017-00008Nemzeti Kutatási Fejlesztési és Innovációs Hivatal GINOP 2.3.2-15-2016-00050 "PEPSYS"Nemzeti Kutatási Fejlesztési és Innovációs Hivatal K123836University of Pécs 17886-4/23018/FEKUTSTRATUniversity of Pécs PTE ÁOK-KA No:2019/KA-2019-31
6 · The paper itself

Abstract

Somatostatin released from the capsaicin-sensitive sensory nerves mediates analgesic and anti-inflammatory effects via the somatostatin sst

Indexed as

Administration, OralAnalgesicsAnimalsCHO CellsChronic DiseaseCricetinaeCricetulusDiterpenesHyperalgesiaInflammationLigandsMaleMiceMolecular Dynamics SimulationNeuralgiaPyrimidinesAnalgesicsDiterpenesLigandspyrimidinePyrimidinesPyrrolesReceptors, Somatostatinresiniferatoxinsomatostatin receptor subtype-4anti-hyperalgesicdockingG-protein activationinflammatory painmolecular modelingneurogenic inflammationneuropathic painresiniferatoxinsst4 receptor

Identifiers

PMID31835716
PMCPMC6940912
OpenAlexW2994848186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.