Evidence map›Paper›PMID 31835712›Full record

ArticleInternational journal of molecular sciences2019

Cloning and Partial Characterization of an Endo-α-(1→6)-d-Mannanase Gene from

Shiva Kumar Angala, Wei Li, Zuzana Palčeková, Lu Zou, Todd L Lowary, Michael R McNeil, Mary Jackson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
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  4. Review
  5. Article
  6. Carbohydrate-Active Enzymes: Structure, Activity, and Reaction Products.International journal of molecular sciences · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Shiva Kumar AngalaMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523-1682, USA.
Wei LiMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523-1682, USA.
Zuzana PalčekováMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523-1682, USA.
Lu ZouDepartment of Chemistry, The University of Alberta, Edmonton, AB T6G 2G2, Canada.
Todd L LowaryDepartment of Chemistry, The University of Alberta, Edmonton, AB T6G 2G2, Canada.ORCID 0000-0002-8331-8211
Michael R McNeilMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523-1682, USA.
Mary JacksonMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523-1682, USA.
Colorado State University · USUniversity of Alberta · CA

Funding

Biogenesis of Lipoarabinomannan in MycobacteriaR01AI064798 · NIAID · COLORADO STATE UNIVERSITY-FORT COLLINS · PI JACKSON, MARY · 2005 to 2019
$5.4M
NIAID NIH HHS R01 AI064798NIH HHS AI064798
6 · The paper itself

Abstract

Mycobacteria produce two major lipoglycans, lipomannan (LM) and lipoarabinomannan (LAM), whose broad array of biological activities are tightly related to the fine details of their structure. However, the heterogeneity of these molecules in terms of internal and terminal covalent modifications and complex internal branching patterns represent significant obstacles to their structural characterization. Previously, an endo-α-(1→6)-D-mannanase from

Indexed as

Cloning, MolecularGenes, BacterialBacillusLipopolysaccharidesMannosidesMannosyltransferasesMycobacterium smegmatisProtein DomainsSubstrate SpecificitylipoarabinomannanlipomannanLipopolysaccharidesMannosidesMannosyltransferasesendo-α-(1→6)-d-mannaselipoarabinomannanlipomannanmannosideMycobacteriumphosphatidylinositol mannosides

Identifiers

PMID31835712
PMCPMC6940960
OpenAlexW2996493498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.