Evidence map›Paper›PMID 31835707›Full record

ReviewAntibiotics (Basel, Switzerland)2019

Re-Understanding the Mechanisms of Action of the Anti-Mycobacterial Drug Bedaquiline.

Jickky Palmae Sarathy, Gerhard Gruber, Thomas Dick

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Bedaquiline Delivery Innovations: A Review on Advancing MDR-TB Treatment Strategies.Recent advances in anti-infective drug discovery · 2025
    Review
  14. Review
  15. Article
  16. Review
  17. Metabolic Rewiring ofMetabolites · 2024
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Jickky Palmae SarathyDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Gerhard GruberSchool of Biological Sciences, Nanyang Technological University, Singapore 637551, Singapore.
Thomas DickCenter for Drug Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ 07110, USA.ORCID 0000-0002-9604-9452
Nanyang Technological University · SGNational University of Singapore · SGSeton Hall University · US

Funding

Discovery of novel lead-target pairs and identification of all-oral bactericidal drug regimens for Mycobacterium abscessus lung diseaseR01AI132374 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI Thomas Dick · 2018 to 2026
$7.0M
National Research Foundation Singapore NRF-CRP18-2017-01NIAID NIH HHS R01 AI132374NIH HHS R01AI132374
6 · The paper itself

Abstract

Bedaquiline (BDQ) inhibits ATP generation in

Indexed as

Bedaquilinec-subunitdiarylquinolineF-ATP synthaseTBAJ-876tuberculosisuncouplerε-subunit

Identifiers

PMID31835707
PMCPMC6963887
OpenAlexW2995910444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.