ArticleInternational journal of molecular sciences2019
Plasma Extracellular Vesicles in Children with OSA Disrupt Blood-Brain Barrier Integrity and Endothelial Cell Wound Healing in Vitro.
Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review of changes in extracellular vesicles associated with obstructive sleep apnoea: implications for diagnosis and treatment.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Chronic Heat Stress Is Associated with Brain Injury, Blood-Brain Barrier Impairment, and Neuroinflammatory Gene Expression in Broilers.Veterinary sciences · 2026Article
- Impact of FASN-enriched EVs on endothelial cell function in obstructive sleep apnea hypopnea syndrome.Journal of pharmaceutical analysis · 2025Article
- Aging, vascular dysfunction, and the blood-brain barrier: unveiling the pathophysiology of stroke in older adults.Biogerontology · 2025Review
- Association between obstructive sleep apnea and Tinnitus in the United States: NHANES 2005-2020.Sleep & breathing = Schlaf & Atmung · 2025Article
- Exosomes regulate SIRT3-related autophagy by delivering miR-421 to regulate macrophage polarization and participate in OSA-related NAFLD.Journal of translational medicine · 2024Article
- Small Extracellular Vesicles Harboring PD-L1 in Obstructive Sleep Apnea.International journal of molecular sciences · 2024Article
- Multi-Omics Analysis of Circulating Exosomes in Adherent Long-Term Treated OSA Patients.International journal of molecular sciences · 2023Article
- Cognitive Impairments, Neuroinflammation and Blood-Brain Barrier Permeability in Mice Exposed to Chronic Sleep Fragmentation during the Daylight Period.International journal of molecular sciences · 2023Article
- Sensitivity to remifentanil and its predictive factor in male patients with moderate to severe obstructive sleep apnea syndrome.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023Article
- Review
- Obstructive Sleep Apnea, Hypercoagulability, and the Blood-Brain Barrier.Journal of clinical medicine · 2021Review
- Cell-Selective Altered Cargo Properties of Extracellular Vesicles Following In Vitro Exposures to Intermittent Hypoxia.International journal of molecular sciences · 2021Article
- The Mystery of Red Blood Cells Extracellular Vesicles in Sleep Apnea with Metabolic Dysfunction.International journal of molecular sciences · 2021Review
- Leakage of astrocyte-derived extracellular vesicles in stress-induced exhaustion disorder: a cross-sectional study.Scientific reports · 2021Article
- Validity and Cost-Effectiveness of Pediatric Home Respiratory Polygraphy for the Diagnosis of Obstructive Sleep Apnea in Children: Rationale, Study Design, and Methodology.Methods and protocols · 2021Article
- Roles of Exosomes and Exosomal MicroRNAs in Postoperative Sleep Disturbance.Nature and science of sleep · 2021Review
- The innate immune toll-like-receptor-2 modulates the depressogenic and anorexiolytic neuroinflammatory response in obstructive sleep apnoea.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Pediatric obstructive sleep apnea (P-OSA) is associated with neurocognitive deficits and endothelial dysfunction, suggesting the possibility that disruption of the blood-brain barrier (BBB) may underlie these morbidities. Extracellular vesicles (EVs), which include exosomes, are small particles involved in cell-cell communications via different mechanisms and could play a role in OSA-associated end-organ injury. To examine the roles of EVs in BBB dysfunction, we recruited three groups of children: (a) absence of OSA or cognitive deficits (CL,
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Registered trials
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