Evidence map›Paper›PMID 31835511›Full record

ReviewMicroorganisms2019

The Dark Side of Microalgae Biotechnology: A Heterotrophic Biorefinery Platform Directed to ω-3 Rich Lipid Production.

Teresa Lopes da Silva, Patrícia Moniz, Carla Silva, Alberto Reis

Abstract readReview
In one paragraph

Review in Microorganisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Color-ModulatedFoods (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
  4. Adaptive Evolution ofMicroorganisms · 2025
    Article
  5. Review
  6. Article
  7. Factors impacting the microbial production of eicosapentaenoic acid.Applied microbiology and biotechnology · 2024
    Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Marine drugs · 2022
    Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Effects of Inclusion ofFoods (Basel, Switzerland) · 2021
    Article
  20. Animals : an open access journal from MDPI · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Teresa Lopes da SilvaLNEG-National Laboratory for the Energy and Geology, I.P.-Bioenergy Unit; Estrada do Paço do Lumiar, 22, Edifício F-R/C, 1649-038 Lisboa, Portugal.
Patrícia MonizLNEG-National Laboratory for the Energy and Geology, I.P.-Bioenergy Unit; Estrada do Paço do Lumiar, 22, Edifício F-R/C, 1649-038 Lisboa, Portugal.
Carla SilvaInstituto Dom Luiz (IDL), Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1747-016 Lisboa, Portugal.ORCID 0000-0002-1439-9214
Alberto ReisLNEG-National Laboratory for the Energy and Geology, I.P.-Bioenergy Unit; Estrada do Paço do Lumiar, 22, Edifício F-R/C, 1649-038 Lisboa, Portugal.

Funding

BONE ALLOGRAFTS FOR SURGICAL ONCOLOGYR01CA030169 · NCI · YALE UNIVERSITY · PI FRIEDLAENDER, GARY E. · 1985 to 1986
–
Fundação para a Ciência e a Tecnologia PTDC/EAM-AMB/30169/2017
6 · The paper itself

Abstract

Microbial oils have been considered a renewable feedstock for bioenergy not competing with food crops for arable land, freshwater and biodiverse natural landscapes. Microalgal oils may also have other purposes (niche markets) besides biofuels production such as pharmaceutical, nutraceutical, cosmetic and food industries. The polyunsaturated fatty acids (PUFAs) obtained from oleaginous microalgae show benefits over other PUFAs sources such as fish oils, being odorless, and non-dependent on fish stocks. Heterotrophic microalgae can use low-cost substrates such as organic wastes/residues containing carbon, simultaneously producing PUFAs together with other lipids that can be further converted into bioenergy, for combined heat and power (CHP), or liquid biofuels, to be integrated in the transportation system. This review analyses the different strategies that have been recently used to cultivate and further process heterotrophic microalgae for lipids, with emphasis on omega-3 rich compounds. It also highlights the importance of studying an integrated process approach based on the use of low-cost substrates associated to the microalgal biomass biorefinery, identifying the best sustainability methodology to be applied to the whole integrated system.

Indexed as

biodieselbioenergydocosahexaenoic acid (DHA)eicosapentaenoic acid (EPA)heterotrophic microalgaelow-cost substrates, circular economysustainability indicators

Identifiers

PMID31835511
PMCPMC6956277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.