Evidence map›Paper›PMID 31835502›Full record

ArticleJournal of clinical medicine2019

Structured Cognitive-Motor Dual Task Training Compared to Single Mobility Training in Persons with Multiple Sclerosis, a Multicenter RCT.

Renee Veldkamp, Ilse Baert, Alon Kalron, Andrea Tacchino, Mieke D'hooge, Ellen Vanzeir, Fanny Van Geel, Joke Raats, Mieke Goetschalckx, Giampaolo Brichetto and 5 more

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06927362 narecruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Lee Silverman Voice Treatment Big and Dual Task Training on Balance, Cognition and Functional Mobility in Older Adults With Cognitive Impairment.

TypeinterventionalSponsorRiphah International UniversityRan2025 to 2025Enrolled50ConditionsCognitive Impairment, Balance Changes, Cognition Disorders in Old Age, Functional MobilityArmsLee Silverman treatment big, Dual task training
NCT07355387 narecruitingnot on this mapstarted 2025, after this paper: background citation

Home Based Functional Balance Intervention (FBI) for Physical and Cognitive Symptoms of Multiple Sclerosis

TypeinterventionalSponsorUniversity of Illinois at ChicagoRan2025 to 2027Enrolled75ConditionsMultiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis (MS) Primary Progressive, Multiple Sclerosis (MS) Secondary ProgressiveArmsMulticomponent balance intervention consisting of four components including dual-tasking, functional strength, vestibular and dynamic balance., Stretching
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Memory rehabilitation for people with multiple sclerosis.The Cochrane database of systematic reviews · 2021
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Review
  12. Article
  13. Article
  14. Article
  15. Advances in Neurodegenerative Diseases.Journal of clinical medicine · 2023
    Article
  16. Review
  17. Article
  18. Cerebellar Contributions to Motor and Cognitive Control in Multiple SclerosisArchives of physical medicine and rehabilitation · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Renee VeldkampREVAL Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, 3500 Hasselt, Belgium.ORCID 0000-0002-7317-2431
Ilse BaertREVAL Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, 3500 Hasselt, Belgium.
Alon KalronDepartment of Physical Therapy, School of Health Professions, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv 6997801, Tel-Aviv, Israel.ORCID 0000-0001-7999-0868
Andrea TacchinoScientific Research Area, Italian MS Foundation (FISM), 16149 Genoa, Italy.ORCID 0000-0002-2263-7315
Mieke D'hoogeREVAL Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, 3500 Hasselt, Belgium.
Ellen VanzeirRehabilitation and MS Center Overpelt, 3900 Pelt, Belgium.
Fanny Van GeelREVAL Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, 3500 Hasselt, Belgium.
Joke RaatsREVAL Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, 3500 Hasselt, Belgium.
Mieke GoetschalckxREVAL Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, 3500 Hasselt, Belgium.
Giampaolo BrichettoScientific Research Area, Italian MS Foundation (FISM), 16149 Genoa, Italy.ORCID 0000-0003-2026-3572
Nov ShalmoniMultiple Sclerosis Center, Sheba Medical Center, Derech Sheba 2, Ramat Gan 5262100, Tel-hashomer, Israel.
Peter HellinckxNational MS Center Melsbroek, 1820 Steenokkerzeel, Belgium.
Natasja De WeerdtRehabilitation and MS Center Overpelt, 3900 Pelt, Belgium.
Dorien De WildeDe Mick AZ Klina, 2930 Brasschaat, Belgium.
Peter FeysREVAL Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, 3500 Hasselt, Belgium.ORCID 0000-0002-5680-5495

Funding

MS Society Flanders R-8153RIMS by Novartis AG R-8153SailingChallenge4MS R-8153Swedish Promobilia Foundation 16067
6 · The paper itself

Abstract

The aim was to compare the effectiveness of dual-task training (DTT) compared to single mobility training (SMT) on dual-task walking, mobility and cognition, in persons with Multiple Sclerosis (pwMS). Forty pwMS were randomly assigned to the DTT or SMT groups. The DTT-group performed dual-task exercises using an interactive tablet-based application, while the SMT-group received conventional walking and balance exercises. Both interventions were supervised and identical in weeks (8) and sessions (20). Nine cognitive-motor dual-task conditions were assessed at baseline, after intervention and at 4-weeks follow-up (FU). The dual-task cost (DTC), percentage change of dual-task performance compared to single-task performance, was the primary outcome. Mobility and cognition were secondarily assessed. Mixed model analyses were done with group, time and the interaction between group and time as fixed factors and participants as random factors. Significant time by group interactions were found for the digit-span walk and subtraction walk dual-task conditions, with a reduction in DTC (gait speed) for the DTT maintained at FU. Further, absolute dual-task gait speed during walking over obstacles only improved after the DTT. Significant improvements were found for both groups in various motor and cognitive measures. However, the DTT led to better dual-task walking compared to the SMT.

Indexed as

balancecognitioncognitive motor interferencedual taskgaitmultiple sclerosis

Identifiers

PMID31835502
PMCPMC6947084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.