Evidence map›Paper›PMID 31835452›Full record

ArticleNutrients2019

Effect of Short-Term Dietary Intervention and Probiotic Mix Supplementation on the Gut Microbiota of Elderly Obese Women.

Raffaella Cancello, Silvia Turroni, Simone Rampelli, Stefania Cattaldo, Marco Candela, Laila Cattani, Stefania Mai, Roberta Vietti, Massimo Scacchi, Patrizia Brigidi and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05364814 (The Effect of Using Probiotic Yogurt on Anthropometric Measurements and Gastrointestinal System in Obese Women), which is not on this map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05364814 completednot on this mapstarted 2022, after this paper: background citation

The Effect of Using Probiotic Yogurt on Anthropometric Measurements and Gastrointestinal System in Obese Women

TypeobservationalSponsorYuksek Ihtisas UniversityRan2022 to 2022Enrolled21ConditionsObesity, Dysbioses
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. The gut microbiome, chronic kidney disease, and sarcopenia.Cell communication and signaling : CCS · 2024
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Potential ofFrontiers in microbiology · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. The gut microbiome as a modulator of healthy ageing.Nature reviews. Gastroenterology & hepatology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Raffaella CancelloDepartment of Medical Sciences and Rehabilitation, IRCCS Istituto Auxologico Italiano, 20145 Milan, Italy.
Silvia TurroniDepartment of Pharmacy and Biotechnology, Unit of Microbial Ecology of Health, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0003-2345-9482
Simone RampelliDepartment of Pharmacy and Biotechnology, Unit of Microbial Ecology of Health, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-5655-6695
Stefania CattaldoLaboratory of Clinical Neurobiology, IRCCS Istituto Auxologico Italiano, 28824 Piancavallo (VB), Italy.
Marco CandelaDepartment of Pharmacy and Biotechnology, Unit of Microbial Ecology of Health, University of Bologna, 40126 Bologna, Italy.
Laila CattaniDivision of Nutritional Rehabilitation, IRCCS Istituto Auxologico Italiano, 28824 Piancavallo (VB), Italy.
Stefania MaiLaboratory of Metabolic Research, IRCCS Istituto Auxologico Italiano, 28824 Piancavallo (VB), Italy.
Roberta ViettiLaboratory of Metabolic Research, IRCCS Istituto Auxologico Italiano, 28824 Piancavallo (VB), Italy.
Massimo ScacchiDivision of Endocrinology and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, 28824 Piancavallo (VB), Italy.ORCID 0000-0002-4624-9114
Patrizia BrigidiDepartment of Pharmacy and Biotechnology, Unit of Microbial Ecology of Health, University of Bologna, 40126 Bologna, Italy.
Cecilia InvittiDepartment of Medical Sciences and Rehabilitation, IRCCS Istituto Auxologico Italiano, 20145 Milan, Italy.
IRCCS Istituto Auxologico Italiano · ITUniversity of Bologna · ITUniversity of Milan · IT

Funding

Ministero della Salute RICCOR number: 2015_12_15_03
6 · The paper itself

Abstract

Accumulating literature is providing evidence that the gut microbiota is involved in metabolic disorders, but the question of how to effectively modulate it to restore homeostasis, especially in the elderly, is still under debate. In this study, we profiled the intestinal microbiota of 20 elderly obese women (EO) at the baseline (T0), after 15 days of hypocaloric Mediterranean diet administered as part of a nutritional-metabolic rehabilitation program for obesity (T1), and after a further 15 days of the same diet supplemented with a probiotic mix (T2). Fecal samples were characterized by Illumina MiSeq sequencing of the 16S rRNA gene. The EO microbiota showed the typical alterations found in obesity, namely, an increase in potential pro-inflammatory components (i.e.,

Indexed as

Diet, MediterraneanAgedAged, 80 and overBiodiversityBody WeightDietary SupplementsDysbiosisFecesFemaleGastrointestinal MicrobiomeHumansMaleObesityProbioticsRNA, Ribosomal, 16SRNA, Ribosomal, 16Selderlygut microbiotaMediterranean dietobesityprobiotics

Identifiers

PMID31835452
PMCPMC6950529
OpenAlexW2993397977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.