Evidence map›Paper›PMID 31835450›Full record

ArticleMolecules (Basel, Switzerland)2019

Antiplasmodial Activity of Nitroaromatic Compounds: Correlation with Their Reduction Potential and Inhibitory Action on

Audronė Marozienė, Mindaugas Lesanavičius, Elisabeth Davioud-Charvet, Alessandro Aliverti, Philippe Grellier, Jonas Šarlauskas, Narimantas Čėnas

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
18.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 95 citations in OpenAlex.

  1. Reactions ofInternational journal of molecular sciences · 2025
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  8. Reactions ofInternational journal of molecular sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Audronė MarozienėDepartment of Xenobiotics Biochemistry, Institute of Biochemistry of Vilnius University, Saulėtekio 7, LT-10257 Vilnius, Lithuania.
Mindaugas LesanavičiusDepartment of Xenobiotics Biochemistry, Institute of Biochemistry of Vilnius University, Saulėtekio 7, LT-10257 Vilnius, Lithuania.
Elisabeth Davioud-CharvetUMR7042 CNRS-Unistra-UHA, Laboratoire d'Innovation Moléculaire et Applications (LIMA), Bioorganic and Medicinal Chemistry Team, European School of Chemistry, Polymers and Materials, 25 rue Becquerel, F-67087 Strasbourg, France.ORCID 0000-0001-7026-4034
Alessandro AlivertiDepartment of Biosciences, Universita degli Studi di Milano, via Celoria 26, I-20133 Milano, Italy.ORCID 0000-0002-1226-3655
Philippe GrellierMCAM, UMR7245, Museum National d'Histoire Naturelle, CNRS, 61 rue Buffon, F-75231 Paris CEDEX 05, France.ORCID 0000-0003-4153-0465
Jonas ŠarlauskasDepartment of Xenobiotics Biochemistry, Institute of Biochemistry of Vilnius University, Saulėtekio 7, LT-10257 Vilnius, Lithuania.ORCID 0000-0003-4268-1716
Narimantas ČėnasDepartment of Xenobiotics Biochemistry, Institute of Biochemistry of Vilnius University, Saulėtekio 7, LT-10257 Vilnius, Lithuania.
Vilnius University · LTCentre National de la Recherche Scientifique · FRUniversity of Milan · IT

Funding

European Science Foundation DOTSUT-34/09.3.3.-LMT-K712-01-0058/LSS-600000-58)
6 · The paper itself

Abstract

With the aim to clarify the mechanism(s) of action of nitroaromatic compounds against the malaria parasite

Indexed as

AntimalarialsAntioxidantsDose-Response Relationship, DrugEnzyme InhibitorsErythrocytesFerredoxin-NADP ReductaseGlutathione ReductaseHumansInhibitory Concentration 50Molecular StructureNADPOxidation-ReductionPlasmodium falciparumAntimalarialsAntioxidantsEnzyme InhibitorsFerredoxin-NADP ReductaseGlutathione ReductaseNADPenzyme inhibitionferredoxin:NADP+ oxidoreductaseglutathione reductasenitroaromaticsPlasmodium falciparum

Identifiers

PMID31835450
PMCPMC6943496
OpenAlexW2993568914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.