Evidence map›Paper›PMID 31835284›Full record

ArticleNeuroImage. Clinical2019

Automatic extraction of the intracranial volume in fetal and neonatal MR scans using convolutional neural networks.

Nadieh Khalili, E Turk, M J N L Benders, P Moeskops, N H P Claessens, R de Heus, A Franx, N Wagenaar, J M P J Breur, M A Viergever and 1 more

Abstract read
In one paragraph

Article in NeuroImage. Clinical, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Fetal-BET: Brain Extraction Tool for Fetal MRI.IEEE open journal of engineering in medicine and biology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Applications of artificial intelligence in obstetrics.Ultrasonography (Seoul, Korea) · 2023
    Article
  14. Review
  15. Article
  16. Article
  17. Rapid head-pose detection for automated slice prescription of fetal-brain MRI.International journal of imaging systems and technology · 2021
    Article
  18. Article
  19. Accurate Estimation of Total Intracranial Volume in MRI using a Multi-tasked Image-to-Image Translation Network.Proceedings of SPIE--the International Society for Optical Engineering · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nadieh KhaliliImage Sciences Institute, Utrecht University and University Medical Center Utrecht, Utrecht, the Netherlands. Electronic address: n.khalili@umcutrecht.nl.
E TurkDepartment of Neonatology, Wilhelmina Childrens Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.
M J N L BendersDepartment of Neonatology, Wilhelmina Childrens Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.
P MoeskopsMedical Image Analysis, Department of Biomedical Engineering, Eindhoven University of Technology, the Netherlands.
N H P ClaessensDepartment of Neonatology, Wilhelmina Childrens Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.
R de HeusDepartment of Obstetrics, University Medical Center Utrecht, the Netherlands.
A FranxDepartment of Obstetrics, University Medical Center Utrecht, the Netherlands.
N WagenaarDepartment of Neonatology, Wilhelmina Childrens Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.
J M P J BreurDepartment of Neonatology, Wilhelmina Childrens Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.
M A ViergeverImage Sciences Institute, Utrecht University and University Medical Center Utrecht, Utrecht, the Netherlands; Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.
I IšgumImage Sciences Institute, Utrecht University and University Medical Center Utrecht, Utrecht, the Netherlands; Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MR images of infants and fetuses allow non-invasive analysis of the brain. Quantitative analysis of brain development requires automatic brain tissue segmentation that is typically preceded by segmentation of the intracranial volume (ICV). Fast changes in the size and morphology of the developing brain, motion artifacts, and large variation in the field of view make ICV segmentation a challenging task. We propose an automatic method for segmentation of the ICV in fetal and neonatal MRI scans. The method was developed and tested with a diverse set of scans regarding image acquisition parameters (i.e. field strength, image acquisition plane, image resolution), infant age (23-45 weeks post menstrual age), and pathology (posthaemorrhagic ventricular dilatation, stroke, asphyxia, and Down syndrome). The results demonstrate that the method achieves accurate segmentation with a Dice coefficient (DC) ranging from 0.98 to 0.99 in neonatal and fetal scans regardless of image acquisition parameters or patient characteristics. Hence, the algorithm provides a generic tool for segmentation of the ICV that may be used as a preprocessing step for brain tissue segmentation in fetal and neonatal brain MR scans.

Indexed as

AlgorithmsBrainDeep LearningFetusHeadHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingNeural Networks, ComputerOrgan SizeBrain extractionBrain segmentationDeep learningFetal MRIIntracranial volume segmentationNeonatal MRISkull stripping

Identifiers

PMID31835284
PMCPMC6909142

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.