ArticleEnvironmental research2020
National secular trends in ambient air volatile organic compound levels and biomarkers of exposure in the United States.
Article in Environmental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The trial behind it
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Who cites it
19 citing papers in PubMed, 53 citations in OpenAlex.
- Mediating role of chronic inflammatory airway diseases in the association between volatile organic compounds exposure and depression.Medicine · 2026Article
- Article
- [Exposures to volatile organic compounds are positively correlated with risks of metabolic dysfunction-associated steatotic liver disease].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026Article
- Exploring the association between volatile organic compound exposure and chronic kidney disease: evidence from explainable machine learning methods.Renal failure · 2025Article
- Clustering environmental pollutants associated with increased risk of metabolic disease: a hierarchical analysis.Health information science and systems · 2025Article
- Associations of sympathetic activation with exposure to volatile organic compounds: A cross-sectional study.Environmental research · 2025Article
- Diminished lung function mediating the associations between blood levels of volatile organic compounds and respiratory morbidity and mortality.Scientific reports · 2025Article
- Article
- Integrating chemical-specific information with general approaches to assessing exposure measurement bias in systematic reviews.Environment international · 2025Article
- Cumulative environmental exposures and metabolic syndrome: A study of heavy metals and volatile organic compounds.Ecotoxicology and environmental safety · 2025Article
- Association of volatile organic compound exposure with metabolic syndrome and its components: a nationwide cross-sectional study.BMC public health · 2024Article
- Associations between specific volatile organic chemical exposures and cardiovascular disease risks: insights from NHANES.Frontiers in public health · 2024Article
- Chloroform associated with bone mineral density and bone mineral content in adults: A population-based cross-sectional research.PloS one · 2024Article
- Methods in Public Health Environmental Justice Research: a Scoping Review from 2018 to 2021.Current environmental health reports · 2023Article
- Environmental exposure to volatile organic compounds is associated with endothelial injury.Toxicology and applied pharmacology · 2022Article
- Feminine Hygiene Products and Volatile Organic Compounds in Reproductive-Aged Women Across the Menstrual Cycle: A Longitudinal Pilot Study.Journal of women's health (2002) · 2022Article
- 1,3-Butadiene: a ubiquitous environmental mutagen and its associations with diseases.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2022Review
- Assessing volatile organic compounds exposure and prostate-specific antigen: National Health and Nutrition Examination Survey, 2001-2010.Frontiers in public health · 2022Article
- Exposure to volatile organic compounds - acrolein, 1,3-butadiene, and crotonaldehyde - is associated with vascular dysfunction.Environmental research · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundExposure to air pollution is a leading cause of global mortality. Volatile organic compounds (VOCs) are constituents of ambient air that could exert adverse health effects.
objectiveTo examine the relationship between VOC levels in ambient air and individual-level exposure to VOCs, as assessed by urinary VOC metabolites.
methodsSecular trends in 11 ambient air VOCs (2005-2013) and individual-level metabolites of 14 VOCs (2005-2014) were assessed using National Monitoring Programs (NMP) and National Health and Nutrition Examination Survey (NHANES) data, respectively. To isolate environmental exposure, individuals reporting exposure to tobacco smoke were excluded. Quantile regression models were used to assess secular trends in VOC exposure, and survey-weighted regression models were built to identify factors associated with VOC exposure.
resultsAll annual levels of ambient VOCs decreased from 2005 to 2013 (Range: 12.5%-77.2%). However, 11 of the corresponding VOC metabolites increased during the same time (Range: 0.3%-53.6%). There was a proportional change in patterns of VOC exposure across NHANES waves, with the middle quantiles of exposure showing the largest increase. VOC exposures were significantly associated with age, sex, race, education, and physical inactivity, but not with secular VOC trends. DISCUSSION: In the United States, individual-level exposure to several VOCs increased between 2005 and 2014 despite a decline in ambient air VOC levels. This inverse relationship suggests that ambient VOCs are not the primary source of VOC exposure, therefore, decreasing ambient VOCs alone may not be sufficient to protect against the adverse health effects associated with VOC exposure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.